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[null,null,null,null,"Ecotoxicity Data Quality Assessment Method V2.4"]
[null,null,null,null,null,"To be used to assess the quality of data used for the Australian and New Zealand Guidelines for Fresh and Marine Water Quality (including sediment) and the Australian National Environment Protection (Assessment of Site Contamination) Measure"]
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[null,null,null,null,null,null,"Developed by "]
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[null,null,null,null,null,null,"Zoe Zhang"]
[null,null,null,null,null,null,"   Dr. Michael Warne"]
[null,null,null,null,null,null,"Alison Vieritz "]
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[]
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[null,null,null,null,null,null,"Water Quality & Investigations "]
[null,null,null,null,null,"                 Department of Science, Information Technology and Innovation"]

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[null,"Click here to see \"All Result\" -->","All Result"]
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[null,null,null,null,"Freshwater "]
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[null,"Tabs contain questionaries -->           ","Freshwater/metal/nonplant",null,"Freshwater/non-metal/non-plant ",null,null,"Freshwater/metal/plant",null,"Freshwater/non-metal/plant"]
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[null,"Tabs contain score of paper and short answers to questions -->","Freshwater/metal/nonplant Worksheet",null,"Freshwater/non-metal/non-plant Worksheet",null,null,"Freshwater/metal/plant Worksheet",null,"Freshwater/non-metal/plant/ Worksheet"]
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[null,null,"Marine ",null,null,null,"Terrestrial",null,null,"Sediment "]
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[null,"Tab contain questionaries -->","Marine or estuarine/non-plant",null,"Marine or estuarine/Plant",null,null,"Terrestrial Data QA",null,"Sediment Data QA"]
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[null,"Tab Contains all scores of paper --> ","Marine or estuarine/non-Plant Worksheet",null,"Marine or estuarine/Plant_Worksheet",null,null,"Terrestrial Quality",null,"Sediment Quality"]

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["Chemical:","Bisphenol A"]
["Medium:","Marine"]
[]
["Category","Paper and data unique identier","Total score","Quality score","Comment ","Species name","Life stage","Exposure duration","Measure of toxicity","Toxicity endpoint","Toxicity value","Taxonomic group","Phylum","Class","Medium","Temperature","Acute or Chronic","pH","Salinity","Citation","Citation No."]
["MEW_nonplant","268-1",80,0.85106382978723405,"","Psammechinus miliaris","Embryo","7 days","NOEC","Reproduction","1500 nM (0.342 mg/L)","Sea urchin","Echinodermata","\tEchinoidea","fresh or artificial seawater","18-20","Chronic","Not stated","30-32 PSU","Anselmo, H.M.R., L. Koerting, S. Devito, J.H.J. van den Berg, M. Dubbeldam, C. Kwadijk and A.J. Murk. 2011. Early life developmental effects of marine persistent organic pollutants on the sea urchin Psammechinus miliaris. Ecotoxicology and Environmental Safety 74: 2182-2192","268"]
["MEW_nonplant","268-2",84,0.8936170212765957,"","Psammechinus miliaris","Larvae","7 days","NOEC","larval development","1500 nM","Sea urchin","Echinodermata","\tEchinoidea","Artificial seawater",19,"Chronic",8,31,"Anselmo, H.M.R., L. Koerting, S. Devito, J.H.J. van den Berg, M. Dubbeldam, C. Kwadijk and A.J. Murk. 2011. Early life developmental effects of marine persistent organic pollutants on the sea urchin Psammechinus miliaris. Ecotoxicology and Environmental Safety 74: 2182-2192","268"]
["MEW_nonplant","268-3",84,0.8936170212765957,"","Psammechinus miliaris","Larvae","14 days","NOEC","larval development","1500 nM","Sea urchin","Echinodermata","\tEchinoidea","Artificial seawater",19,"Chronic",8,31,"Anselmo, H.M.R., L. Koerting, S. Devito, J.H.J. van den Berg, M. Dubbeldam, C. Kwadijk and A.J. Murk. 2011. Early life developmental effects of marine persistent organic pollutants on the sea urchin Psammechinus miliaris. Ecotoxicology and Environmental Safety 74: 2182-2192","268"]
["MEW_nonplant","269-1",68,0.72340425531914898,"The highest possible grade for this datum is acceptable.","Hemicentrotus pulcherrimus","juvenile","80 days","LOEC","Growth","0.5 uM (0.114 mg/L)","Sea urchin","Echinodermata","\tEchinoidea","seawater",18,"Chronic","Not stated","Not stated","Kiyomoto, M., A. Kikuchi, T. Unuma and Y. Yokota. 2006. Effects of ethynlyestradiol and bisphenol A on the development of sea urchin embryos and juveniles. Marine Biology 149: 57-63.","269"]
["MEW_nonplant","270-1",71,0.75531914893617025,"The highest possible grade for this datum is acceptable.","Acartia tonsa","adult","2 days","LC10","Mortality","800 µg/L","Copepoda","Arthropoda","Maxillopoda","Artificial seawater",20,"Acute","not stated",0.18,"Andersen, H.R., L. Wollenberger, B. Halling-Sorensen and K.O. Kusk. 2001. Development of copepod nauplii to copepodites - a parameter for chronic toxicity including endocrine disruption. Environmental Toxicology and Chemistry 20: 2821-2829.","270"]
["MEW_nonplant","270-2",71,0.75531914893617025,"The highest possible grade for this datum is acceptable.","Acartia tonsa","adult","2 days","LC50","Mortality","4200 µg/L","Copepoda","Arthropoda","Maxillopoda","Artificial seawater",20,"Acute","not stated",0.18,"Andersen, H.R., L. Wollenberger, B. Halling-Sorensen and K.O. Kusk. 2001. Development of copepod nauplii to copepodites - a parameter for chronic toxicity including endocrine disruption. Environmental Toxicology and Chemistry 20: 2821-2829.","270"]
["MEW_nonplant","270-3",71,0.75531914893617025,"The highest possible grade for this datum is acceptable.","Acartia tonsa","Nauplii (larvae)","5 days","EC10","Growth - development","0.1 mg/L","Copepoda","Arthropoda","Maxillopoda","Artificial seawater","19.5-20.5","Acute","Not stated","18 ppt","Andersen, H.R., L. Wollenberger, B. Halling-Sorensen and K.O. Kusk. 2001. Development of copepod nauplii to copepodites - a parameter for chronic toxicity including endocrine disruption. Environmental Toxicology and Chemistry 20: 2821-2829.","270"]
["MEW_nonplant","270-4",76,0.80851063829787229,"The highest possible grade for this datum is acceptable.","Acartia tonsa","Nauplii (larvae)","5 days","EC10","Development","100 µg/L","Copepoda","Arthropoda","Maxillopoda","Artificial seawater",20,"Chronic","not stated",0.18,"Andersen, H.R., L. Wollenberger, B. Halling-Sorensen and K.O. Kusk. 2001. Development of copepod nauplii to copepodites - a parameter for chronic toxicity including endocrine disruption. Environmental Toxicology and Chemistry 20: 2821-2829.","270"]
["MEW_nonplant","271-1",83,0.88297872340425532,"The highest possible grade for this datum is acceptable.","Tigriopus japonicus","Adult","4 days","NOEC","Survival","0.1 mg/L","Crustacean","Arthropoda","Maxillopoda","seawater","19-21","Acute",7.90,"32 o/00","Lee, K.W., S. Raisuddin, D.S. Hwang, H.G. Park and J.S. Lee. 2007. Acute toxicities of trace metals and common xenobiotics to the marine copepod Tigriopus japonicus: Evaluation of its Use as a Benchmark Species for Routine Ecotoxicity Tests in Western Pacific Coastal Regions. Environmental Toxicology 22: 532-538","271"]
["MEW_nonplant","271-2",83,0.88297872340425532,"The highest possible grade for this datum is acceptable.","Tigriopus japonicus","adult","4 days","LC10","Mortality","110 µg/L","Copepoda","Arthropoda","Maxillopoda","seawater UV treated natural",20,"Acute",7.90,32,"Lee, K.W., S. Raisuddin, D.S. Hwang, H.G. Park and J.S. Lee. 2007. Acute toxicities of trace metals and common xenobiotics to the marine copepod Tigriopus japonicus: Evaluation of its Use as a Benchmark Species for Routine Ecotoxicity Tests in Western Pacific Coastal Regions. Environmental Toxicology 22: 532-538","271"]
["MEW_nonplant","271-3",83,0.88297872340425532,"The highest possible grade for this datum is acceptable.","Tigriopus japonicus","adult","4 days","LC50","Mortality","200 µg/L","Copepoda","Arthropoda","Maxillopoda","seawater UV treated natural",20,"Acute",7.90,32,"Lee, K.W., S. Raisuddin, D.S. Hwang, H.G. Park and J.S. Lee. 2007. Acute toxicities of trace metals and common xenobiotics to the marine copepod Tigriopus japonicus: Evaluation of its Use as a Benchmark Species for Routine Ecotoxicity Tests in Western Pacific Coastal Regions. Environmental Toxicology 22: 532-538","271"]
["MEW_nonplant","272-1",69,0.73404255319148937,"The highest possible grade for this datum is acceptable.","Strongylocentrotus purpuratus","Larvae","4 days","EC50","Growth - development","0.2265 mg/L","Sea urchin","Echinodermata","\tEchinoidea","Seawater and solvent",17,"Acute","Not stated","Not stated","Roepke, T.A., M.J. Synder and G.N. Cherr. 2005. Estradiol and endocrine disrupting compounds adversely affect development of sea urchin embryos at environmentally relevant concentrations. Aquatic Toxicology 71: 155-173","272"]
["MEW_nonplant","280-1",72,0.76595744680851063,"The highest possible grade for this datum is acceptable.","Homarus americanus","Larvae","25 day","LOEC","Growth - development","0.000005 mg/L (0.005 ug/L)","Lobster","Euarthropoda","Malacostraca","unfiltered seawater","16-18","Chronic","Not stated","32 g/L","Laufer, H., B. Baclaski and U. Koehn. 2012. Alkylphenols affect lobster (Homarus americanus) larval survival, molting and metamorphosis. Invertebrate Reproduction and Development 56: 66-71","280"]
["MEW_nonplant","280-2",75,0.7978723404255319,"The highest possible grade for this datum is acceptable.","Homarus americanus","Larvae","25 day","LOEC","Mortality","0.005 µg/L","Crustacean","Arthropoda","Malacostraca","seawater",17,"Chronic","Not stated","32 g/L","Laufer, H., B. Baclaski and U. Koehn. 2012. Alkylphenols affect lobster (Homarus americanus) larval survival, molting and metamorphosis. Invertebrate Reproduction and Development 56: 66-71","280"]
["MEW_nonplant","281-1",70,0.74468085106382975,"The highest possible grade for this datum is acceptable.","Americamysis bahia","Larvae","4 days","LC50","Survival","1.03 mg/L","Crustacean","Arthropoda","Malacostraca","Seawater and solvent","24-26","Acute","Not stated","25 o/00 ","Hirano, M., H. Ishibashi, N. Matsumura, Y. Nagao, N. Watanabe, A. Watanabe, N. Onikura, K. Kishi and K. Arizono. 2004. Acute toxicity responses of two crustaceans, Americamysis bahia and Daphnia magna, to endocrine disruptors. Journal of Health Science 50: 97-100.","281"]
["MEW_nonplant","282-1",68,0.72340425531914898,"The highest possible grade for this datum is acceptable.","Oryzias melastigma","Larvae","14 days","LOEC","Growth - body length and width","0.2 mg/L","Fish ","Chordata","\tActinopterygii","Seawater and solvent","27-29","Chronic","Not stated","30 o/00","Huang, Q., C. Fang, Y. Chen, X. Wu, T. Ye, Y. Lin and S. Dong. 2012. Embryonic exposure to low concentration of bisphenol A affects the development of Orzyias melastigma larvae. Environmental Science and Pollution Research 19: 2506-2514","282"]
["MEW_plant","287-2",77,0.84615384615384615,"","Skeletonema costatum","not stated","96 hrs","EC50","Population Abundance: Biomass (Chl-a)","1800 µg/L","Diatom","Bacillariophyta","Mediophyceae","Saltwater algal assay medium",20,"Chronic","Not stated",20,"Alexander, H.C., D. C. Dill, L.W. Smith, P.D. Guiney and P. Dorn. 1988. Bisphenol A: Acute Aquatic Toxicity. Environmental Toxicology and Chemistry 7: 19-26.","287"]
["MEW_nonplant","287-3",87,0.92553191489361697,"","Mysidopsis bahia","Larvae","4 days","LC50","Survival","1.1 mg/L","Crustacean","Arthropoda","Malacostraca","seawater","24-26","Acute","7.5-8.1","20 ppt","Alexander, H.C., D.C. Dill, L.W. Smith, P.D. Guiney and P. Dorn. 1988. Bisphenol A: Acute Aquatic Toxicity. Environmental Toxicology and Chemistry 7: 19-26","287"]
["MEW_nonplant","287-4",90,0.95744680851063835,"","Menidia menidia","Larvae","4 days","LC50","Survival","9.4 mg/L","Fish ","Chordata","\tActinopterygii","seawater","21-23","Acute","7.9-8.2","20 ppt","Alexander, H.C., D.C. Dill, L.W. Smith, P.D. Guiney and P. Dorn. 1988. Bisphenol A: Acute Aquatic Toxicity. Environmental Toxicology and Chemistry 7: 19-26","287"]
["MEW_nonplant","3501-1",72,0.76595744680851063,"The highest possible grade for this datum is acceptable.","Paracentrotus lividus","embryo","72 h","EC1","Development",273,"Macroinvertebrate","Echinodermata","\tEchinoidea","filtered sea water","18±2","Chronic","Not stated",35,"Özlem, Ç.A., Hatice, P. (2008). Effects of bisphenol A on the embryonic development of sea urchin (Paracentrotus lividus). Environmental Toxicology 23, 387-392.","9001"]
["MEW_nonplant","3501-2",72,0.76595744680851063,"The highest possible grade for this datum is acceptable.","Paracentrotus lividus","embryo","72 h","EC5","Development",362,"Macroinvertebrate","Echinodermata","\tEchinoidea","filtered sea water","18±2","Chronic","Not stated",35,"Özlem, Ç.A., Hatice, P. (2008). Effects of bisphenol A on the embryonic development of sea urchin (Paracentrotus lividus). Environmental Toxicology 23, 387-392.","9001"]
["MEW_nonplant","3501-3",72,0.76595744680851063,"The highest possible grade for this datum is acceptable.","Paracentrotus lividus","embryo","72 h","EC10","Development",420,"Macroinvertebrate","Echinodermata","\tEchinoidea","filtered sea water","18±2","Chronic","Not stated",35,"Özlem, Ç.A., Hatice, P. (2008). Effects of bisphenol A on the embryonic development of sea urchin (Paracentrotus lividus). Environmental Toxicology 23, 387-392.","9001"]
["MEW_nonplant","3501-5",63,0.67021276595744683,"The highest possible grade for this datum is acceptable.","Paracentrotus lividus","embryo","72 h","LOEC","Embryonic development",300,"Macroinvertebrate","Echinodermata","\tEchinoidea","filtered sea water","18±2","Chronic","Not stated",35,"Özlem, Ç.A., Hatice, P. (2008). Effects of bisphenol A on the embryonic development of sea urchin (Paracentrotus lividus). Environmental Toxicology 23, 387-392.","9001"]
["MEW_nonplant","3502-1",85,0.9042553191489362,"","Haliotis diversicolor supertexta","Fertilised eggs","96 hr","EC5","embryonic/larval growth","0.21 µg/L","Macroinvertebrate","Mollusca","Gastropoda","Seawater filtered through a Whatman GF/B filtration memberane ","25 ± 1°C","Chronic",8.10,30,"Liu,Y., N.F.Y. Tam, Y. Guan, M. Yasojima, J. Zhou, and B. Gao, 2011 Acute Toxicity of Nonylphenols and Bisphenol A to the Embryonic Development of the Abalone Haliotis diversicolor supertexta. Ecotoxicology20(6): 1233-1245","3502"]
["MEW_nonplant","3502-2",85,0.9042553191489362,"","Haliotis diversicolor supertexta","Fertilised eggs","96 hr","EC5","embryonic/larval growth","0.18 µg/L","Macroinvertebrate","Mollusca","Gastropoda","Seawater filtered through a Whatman GF/B filtration memberane ","25 ± 1°C","Chronic",8.10,30,"Liu,Y., N.F.Y. Tam, Y. Guan, M. Yasojima, J. Zhou, and B. Gao, 2011 Acute Toxicity of Nonylphenols and Bisphenol A to the Embryonic Development of the Abalone Haliotis diversicolor supertexta. Ecotoxicology20(6): 1233-1245","3502"]
["MEW_nonplant","3502-3",85,0.9042553191489362,"","Haliotis diversicolor supertexta","Fertilised eggs","96 hr","EC50","embryonic/larval growth","1.02 µg/L","Macroinvertebrate","Mollusca","Gastropoda","Seawater filtered through a Whatman GF/B filtration memberane ","25 ± 1°C","Chronic",8.10,30,"Liu,Y., N.F.Y. Tam, Y. Guan, M. Yasojima, J. Zhou, and B. Gao, 2011 Acute Toxicity of Nonylphenols and Bisphenol A to the Embryonic Development of the Abalone Haliotis diversicolor supertexta. Ecotoxicology20(6): 1233-1245","3502"]
["MEW_nonplant","3502-4",85,0.9042553191489362,"","Haliotis diversicolor supertexta","Fertilised eggs","96 hr","EC50","embryonic/larval growth","1.67 µg/L","Macroinvertebrate","Mollusca","Gastropoda","Seawater filtered through a Whatman GF/B filtration memberane ","25 ± 1°C","Chronic",8.10,30,"Liu,Y., N.F.Y. Tam, Y. Guan, M. Yasojima, J. Zhou, and B. Gao, 2011 Acute Toxicity of Nonylphenols and Bisphenol A to the Embryonic Development of the Abalone Haliotis diversicolor supertexta. Ecotoxicology20(6): 1233-1245","3502"]
["MEW_nonplant","3502-5",85,0.9042553191489362,"","Haliotis diversicolor supertexta","Fertilised eggs","12 hours","EC5","embryonic/larval growth","13.93 µg/L","Macroinvertebrate","Mollusca","Gastropoda","Seawater filtered through a Whatman GF/B filtration memberane ","25 ± 1°C","Acute",8.10,30,"Liu,Y., N.F.Y. Tam, Y. Guan, M. Yasojima, J. Zhou, and B. Gao, 2011 Acute Toxicity of Nonylphenols and Bisphenol A to the Embryonic Development of the Abalone Haliotis diversicolor supertexta. Ecotoxicology20(6): 1233-1245","3502"]
["MEW_nonplant","3502-6",85,0.9042553191489362,"","Haliotis diversicolor supertexta","Fertilised eggs","12 hours","EC50","embryonic/larval growth","30.72 µg/L","Macroinvertebrate","Mollusca","Gastropoda","Seawater filtered through a Whatman GF/B filtration memberane ","25 ± 1°C","Acute",8.10,30,"Liu,Y., N.F.Y. Tam, Y. Guan, M. Yasojima, J. Zhou, and B. Gao, 2011 Acute Toxicity of Nonylphenols and Bisphenol A to the Embryonic Development of the Abalone Haliotis diversicolor supertexta. Ecotoxicology20(6): 1233-1245","3502"]
["MEW_nonplant","3503-1",63,0.67021276595744683,"The highest possible grade for this datum is acceptable.","Paracentrotus lividus","Egg","30 minutes","EC50","Development","388 µg/L","macroinvertebrate","Echinodermata","\tEchinoidea","0.2 µM Filtered Seawater",16,"Acute","Not stated","Not stated","Bosnjak,I., M. Borra, F. Iamunno, G. Benvenuto, I. Ujevic, I. Buselic, R. Roje-Busatto, and I. Mladineo 2014 Effect of Bisphenol A on P-Glycoprotein-Mediated Efflux and Ultrastructure of the Sea Urchin Embryo Aquat. Toxicol.156:21-29","3503"]
["MEW_nonplant","3504-1",73,0.77659574468085102,"The highest possible grade for this datum is acceptable.","Psammechinus miliaris","Egg","15 minutes","NOEC","Reproduction: Fertility","438 µM","Macroinvertebrate","Echinodermata","\tEchinoidea","seawater",18,"Acute","Not stated","Not stated","Schafer,S., U. Bickmeyer, and A. Koehler 2009 Measuring Ca2+-Signalling at Fertilization in the Sea Urchin Psammechinus miliaris: Alterations of this Ca2+-Signal by Copper and 2,4,6-Tribromophenol Comp. Biochem. Physiol. C Comp. Pharmacol. Toxicol.150(2): 261-269","3504"]
["MEW_nonplant","741-1",76,0.80851063829787229,"The highest possible grade for this datum is acceptable.","Artemia salina","Not stated","1 day","EC50","Survival","56.1 mg/L","Crustacean","Arthropoda","Artemiidae","Artificial seawater",25,"Acute","7.6-8.0","Not stated","Kalcikova, G., J. Zagorc-Koncan and A.Z. Gotvajn. 2012. Artemia salina acute immobilization test: a possible tool for aquatic ecotoxicity assessment. Water Science and Technology 66.4: 903-908","741"]
["MEW_nonplant","743-1",71,0.75531914893617025,"The highest possible grade for this datum is acceptable.","Prorocentrum cordatum (formerly Prorocentrum minimum)","Not stated","3 days","EC50","Growth","1.51 mg/L","Algae","Myzozoa","Dinophyceae","seawater",20,"Acute","Not stated","Not stated","Guo, R., V. Ebenezer and J.S. Ki. 2012. Transcriptional responses of heat shock protein 70 (Hsp70) to thermal, bisphenol A, and copper stresses in the dinoflagellate Prorocentrum minimum. Chemosphere 89: 512-520","743"]
["MEW_nonplant","744-1",71,0.75531914893617025,"The highest possible grade for this datum is acceptable.","Haliotis diversicolor supertexta","Adult","5 days","NOEC","Development","0.05 mg/L","Abalone","Mollusca","Haliotidae","sand filtered seawater","22-26","Acute","7.8-8.2","28-32 %","Zhou, J., Z.S. Zhu and Z.H. Cai. 2011. The impacts of bisphenol A (BPA) on abalone (Haliotis diversicolor supertexta) embryonic development. Chemosphere 82: 443-450","744"]
["MEW_nonplant","744-2",71,0.75531914893617025,"The highest possible grade for this datum is acceptable.","Haliotis diversicolor supertexta","female mature","5 day","NOEC","Development","200 ug/L","Abalone","Mollusca","Gastropoda","sand filtered seawater",24,"Acute",8,30,"Zhou, J., Z.S. Zhu and Z.H. Cai. 2011. The impacts of bisphenol A (BPA) on abalone (Haliotis diversicolor supertexta) embryonic development. Chemosphere 82: 443-450","744"]
["MEW_nonplant","745-1",65,0.69148936170212771,"The highest possible grade for this datum is acceptable.","Tigriopus japonicus","Nauplii (larvae)","21 days","NOEC","Development","0.00001 mg/L","Crustacean","Arthropoda","Maxillopoda","seawater",25,"Chronic","Not stated","25 ppt","Marcial, H.S., A. Hagiwara and T.W. Snell. 2003. Estrogenic compounds affect development of harpaticoid copepod Tigriopus japonicus. Environmental Toxicology and Chemistry 22: 3025-3030.","745"]
["MEW_nonplant","742-1",74,0.78723404255319152,"The highest possible grade for this datum is acceptable.","Margalefidinium polykrikoides (formerly Cochlodinium polykrikoides)","Exponential growth phase","3 days","EC10","Cell counts","3.47 mg/L","Dinoflagellate","Myzozoa ","Dinophyceae","filtered sea water","Not stated","Chronic","Not stated","not stated","Ebenezer V. and J.S. Ki. 2012. Evaluation of the sub-lethal toxicity of Cu, Pb, bisphenol A and polychlorinated biphenyl to the marine dinoflagellate Cochlodinium polykrikoides. Algae 27: 63-70","742"]
["MEW_nonplant","742-2",74,0.78723404255319152,"The highest possible grade for this datum is acceptable.","Margalefidinium polykrikoides (formerly Cochlodinium polykrikoides)","Exponential growth phase","3 days","EC50","Cell counts","68150 ug/L","Dinoflagellate","Myzozoa ","Dinophyceae","filtered sea water","Not stated","Chronic","Not stated","not stated","Ebenezer V. and J.S. Ki. 2012. Evaluation of the sub-lethal toxicity of Cu, Pb, bisphenol A and polychlorinated biphenyl to the marine dinoflagellate Cochlodinium polykrikoides. Algae 27: 63-70","742"]
["MEW_plant","287-1",77,0.84615384615384615,"The highest possible grade for this datum is acceptable.","Skeletonema costatum","N.A.","4 days","EC50","Cell counts","1 mg/L","N.A.","Ochrophyta","Bacillariophyceae","Saltwater algal assay medium","20+/-2","N.A.","N.A.","20 ppt","Alexander, H.C., D.C. Dill, L.W. Smith, P.D. Guiney and P. Dorn. 1988. Bisphenol A: Acute Aquatic Toxicity. Environmental Toxicology and Chemistry 7: 19-26","287"]
["MEW_plant","291-1",69,0.75824175824175821,"","Skeletonema costatum","N.A.","3 days","EC50","Growth","0.55 mg/L","N.A.","Ochrophyta","Bacillariophyceae","Natural and artificial seawater","N.A.","N.A.","N.A.","30 ppt","Walsh, G.E., M.J. Yoder, L.L. McLaughlin and E.M. Lores. 1987. Response of marine unicellular algae to brominated organic compounds in six growth media. Ecotoxicology and Environmental Safety 14: 215-222","291"]
["MEW_plant","291-2",77,0.84615384615384615,"","Chlorella sp.","N.A.","3 days","EC50","Growth","0.83 mg/L","N.A.","Chlorophyta","Trebouxiophyceae","Natural and artificial seawater","N.A.","N.A.","N.A.","30 ppt","Walsh, G.E., M.J. Yoder, L.L. McLaughlin and E.M. Lores. 1987. Response of marine unicellular algae to brominated organic compounds in six growth media. Ecotoxicology and Environmental Safety 14: 215-222","291"]

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[{"$f":"'MEW nonplant'!B11","v":"No."},{"$f":"'MEW nonplant'!B13","v":1},{"$f":"'MEW nonplant'!B16","v":2},{"$f":"'MEW nonplant'!B19","v":3},{"$f":"'MEW nonplant'!B21","v":4},{"$f":"'MEW nonplant'!B23","v":5},{"$f":"'MEW nonplant'!B26","v":6},{"$f":"'MEW nonplant'!B29","v":7},{"$f":"'MEW nonplant'!B32","v":8},{"$f":"'MEW nonplant'!B35","v":9},{"$f":"'MEW nonplant'!B39","v":10},{"$f":"'MEW nonplant'!B42","v":11},{"$f":"'MEW nonplant'!B45","v":12},{"$f":"'MEW nonplant'!B48","v":13},{"$f":"'MEW nonplant'!B51","v":14},{"$f":"'MEW nonplant'!B53","v":15},{"$f":"'MEW nonplant'!B58","v":16.10},{"$f":"'MEW nonplant'!B61","v":16.20},{"$f":"'MEW nonplant'!B64","v":16.30},{"$f":"'MEW nonplant'!B67","v":17},{"$f":"'MEW nonplant'!B70","v":18},{"$f":"'MEW nonplant'!C75","v":"Total score"},{"$f":"'MEW nonplant'!C77","v":"Quality Score"}]
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[{"$f":"'MEW nonplant'!H11","v":"Answers"},{"$f":"IF('MEW nonplant'!H12=\"\",\"\",'MEW nonplant'!H12)","v":"3 days"},{"$f":"IF('MEW nonplant'!H15=\"\",\"\",'MEW nonplant'!H15)","v":"cell counts"},{"$f":"IF('MEW nonplant'!H18=\"\",\"\",'MEW nonplant'!H18)","v":"EC50"},{"$f":"IF('MEW nonplant'!H21=\"\",\"\",'MEW nonplant'!H21)","v":0.50},{"$f":"IF('MEW nonplant'!H23=\"\",\"\",'MEW nonplant'!H23)","v":"Filtered seawater"},{"$f":"IF('MEW nonplant'!H26=\"\",\"\",'MEW nonplant'!H26)","v":"Yes"},{"$f":"IF('MEW nonplant'!H29=\"\",\"\",'MEW nonplant'!H29)","v":"OECD guidelines "},{"$f":"IF('MEW nonplant'!#REF!=\"\",\"\",'MEW nonplant'!#REF!)","v":{"$error":"#REF!"}},{"$f":"IF('MEW nonplant'!H35=\"\",\"\",'MEW nonplant'!H35)","v":"Filtered seawater supplemented with macronutrients, vitamins and trace metals"},{"$f":"IF('MEW nonplant'!H38=\"\",\"\",'MEW nonplant'!H38)","v":"static"},{"$f":"IF('MEW nonplant'!H41=\"\",\"\",'MEW nonplant'!H41)","v":"Not stated"},{"$f":"IF('MEW nonplant'!H44=\"\",\"\",'MEW nonplant'!H44)","v":"Not stated"},{"$f":"IF('MEW nonplant'!H47=\"\",\"\",'MEW nonplant'!H47)","v":"Table 2"},{"$f":"IF('MEW nonplant'!H50=\"\",\"\",'MEW nonplant'!H50)","v":""},{"$f":"IF('MEW nonplant'!H53=\"\",\"\",'MEW nonplant'!H53)","v":""},{"$f":"IF('MEW nonplant'!H57=\"\",\"\",'MEW nonplant'!H57)","v":""},{"$f":"IF('MEW nonplant'!H60=\"\",\"\",'MEW nonplant'!H60)","v":""},{"$f":"IF('MEW nonplant'!H63=\"\",\"\",'MEW nonplant'!H63)","v":""},{"$f":"IF('MEW nonplant'!H66=\"\",\"\",'MEW nonplant'!H66)","v":"20oC"},{"$f":"IF('MEW nonplant'!H69=\"\",\"\",'MEW nonplant'!H69)","v":"Analytica grade reagent; Cat no. A133027; Sigma-Aldrich"}]
[{"$f":"'MEW nonplant'!G3","v":"Species (Scientific name)"},{"$f":"'MEW nonplant'!G4","v":"Lifestage"},{"$f":"'MEW nonplant'!G5","v":"Exposure duration"},{"$f":"'MEW nonplant'!G6","v":"Measure of toxicity"},{"$f":"'MEW nonplant'!G7","v":"Toxicity endpoint"},{"$f":"'MEW nonplant'!G8","v":"Toxicity value"},{"$f":"'MEW nonplant'!J2","v":"Taxonomic group"},{"$f":"'MEW nonplant'!J3","v":"Phylum"},{"$f":"'MEW nonplant'!J4","v":"Class"},{"$f":"'MEW nonplant'!J5","v":"Media"},{"$f":"'MEW nonplant'!J6","v":"Temperature "},{"$f":"'MEW nonplant'!J7","v":"Acute Or Chronic "},{"$f":"'MEW nonplant'!J8","v":"PH"},{"$f":"'MEW nonplant'!J9","v":"Salinity/Conductivity"},{"$f":"'MEW nonplant'!C4","v":"Citation"},{"$f":"'MEW nonplant'!G2","v":"Citation No."}]
[{"$f":"'MEW nonplant'!Q3","v":"Cochlodinium polykrikoides"},{"$f":"'MEW nonplant'!T3","v":"Exponential growth phase"},{"$f":"'MEW nonplant'!W3","v":"3 days"},{"$f":"'MEW nonplant'!Z3","v":"EC50"},{"$f":"'MEW nonplant'!AC3","v":"Cell counts"},{"$f":"IF('MEW nonplant'!H8=\"\",\"\",'MEW nonplant'!H8)","v":"68150 ug/L"},{"$f":"'MEW nonplant'!AF3","v":"Dinoflagellate"},{"$f":"'MEW nonplant'!AI3","v":"Miozoa"},{"$f":"'MEW nonplant'!AL3","v":"Dinophyceae"},{"$f":"'MEW nonplant'!AO3","v":"filtered sea water"},{"$f":"'MEW nonplant'!AR3","v":"Not stated"},{"$f":"'MEW nonplant'!AU3","v":"Chronic"},{"$f":"'MEW nonplant'!AX3","v":"Not stated"},{"$f":"'MEW nonplant'!BA3","v":"not stated"},{"$f":"IF('MEW nonplant'!E4=\"\",\"\",'MEW nonplant'!E4)","v":"Ebenezer V. and J.S. Ki. 2012. Evaluation of the sub-lethal toxicity of Cu, Pb, bisphenol A and polychlorinated biphenyl to the marine dinoflagellate Cochlodinium polykrikoides. Algae 27: 63-70"},{"$f":"IF('MEW nonplant'!H2=\"\",\"\",'MEW nonplant'!H2)","v":"742"}]
[{"$f":"'MEW plant'!B11","v":"No."},{"$f":"'MEW plant'!B13","v":1},{"$f":"'MEW plant'!B16","v":2},{"$f":"'MEW plant'!B19","v":3},{"$f":"'MEW plant'!B21","v":4},{"$f":"'MEW plant'!B23","v":5},{"$f":"'MEW plant'!B26","v":6},{"$f":"'MEW plant'!B29","v":7},{"$f":"'MEW plant'!B32","v":8},{"$f":"'MEW plant'!B35","v":9},{"$f":"'MEW plant'!B39","v":10},{"$f":"'MEW plant'!B42","v":11},{"$f":"'MEW plant'!B45","v":12},{"$f":"'MEW plant'!B48","v":13},{"$f":"'MEW plant'!B51","v":14},{"$f":"'MEW plant'!B53","v":15},{"$f":"'MEW plant'!B57","v":16.10},{"$f":"'MEW plant'!B61","v":16.20},{"$f":"'MEW plant'!B64","v":17},{"$f":"'MEW plant'!B67","v":18},{"$f":"'MEW plant'!C72","v":"Total score"},{"$f":"'MEW plant'!C74","v":"Quality Score"}]
[{"$f":"'MEW plant'!C2","v":"Category"},{"$f":"'MEW plant'!E2","v":"MEW_plant"},{"$f":"'MEW plant'!C3","v":"Paper and data unique identifier(eg. 1-1,10-150)"},{"$f":"'MEW plant'!E3","v":"291-2"}]
[{"$f":"'MEW plant'!G11","v":"Scores"},{"$f":"'MEW plant'!G12","v":10},{"$f":"'MEW plant'!G15","v":10},{"$f":"'MEW plant'!G18","v":5},{"$f":"'MEW plant'!G21","v":5},{"$f":"'MEW plant'!G23","v":5},{"$f":"'MEW plant'!G26","v":5},{"$f":"'MEW plant'!G29","v":0},{"$f":"'MEW plant'!G32","v":5},{"$f":"'MEW plant'!G35","v":5},{"$f":"'MEW plant'!G38","v":4},{"$f":"'MEW plant'!G41","v":4},{"$f":"'MEW plant'!G44","v":4},{"$f":"'MEW plant'!G47","v":4},{"$f":"'MEW plant'!G50","v":4},{"$f":"'MEW plant'!G53","v":4},{"$f":"'MEW plant'!G57","v":3},{"$f":"'MEW plant'!G61","v":0},{"$f":"'MEW plant'!G64","v":0},{"$f":"'MEW plant'!G67","v":0},{"$f":"'MEW plant'!G72","v":77},{"$f":"'MEW plant'!G74","v":0.84615384615384615},{"$f":"'MEW plant'!H74","v":""}]
[{"$f":"'MEW plant'!H11","v":"Answers"},{"$f":"IF('MEW plant'!H12=\"\",\"\",'MEW plant'!H12)","v":"3 days"},{"$f":"IF('MEW plant'!H15=\"\",\"\",'MEW plant'!H15)","v":"Growth - cell counts"},{"$f":"IF('MEW plant'!H18=\"\",\"\",'MEW plant'!H18)","v":"EC50"},{"$f":"IF('MEW plant'!H21=\"\",\"\",'MEW plant'!H21)","v":"EC50"},{"$f":"IF('MEW plant'!H23=\"\",\"\",'MEW plant'!H23)","v":"Natural and artificial seawater"},{"$f":"IF('MEW plant'!H26=\"\",\"\",'MEW plant'!H26)","v":"Assume yes as based on Walsh and Alexander"},{"$f":"IF('MEW plant'!H29=\"\",\"\",'MEW plant'!H29)","v":""},{"$f":"IF('MEW plant'!H32=\"\",\"\",'MEW plant'!H32)","v":"Culture source obtained"},{"$f":"IF('MEW plant'!H35=\"\",\"\",'MEW plant'!H35)","v":"Natural and artificial seawater"},{"$f":"IF('MEW plant'!H38=\"\",\"\",'MEW plant'!H38)","v":"Static"},{"$f":"IF('MEW plant'!H41=\"\",\"\",'MEW plant'!H41)","v":"HPLC"},{"$f":"IF('MEW plant'!H44=\"\",\"\",'MEW plant'!H44)","v":"No - not stated"},{"$f":"IF('MEW plant'!H47=\"\",\"\",'MEW plant'!H47)","v":""},{"$f":"IF('MEW plant'!H50=\"\",\"\",'MEW plant'!H50)","v":"Yes"},{"$f":"IF('MEW plant'!H53=\"\",\"\",'MEW plant'!H53)","v":"Yes "},{"$f":"IF('MEW plant'!H60=\"\",\"\",'MEW plant'!H60)","v":""},{"$f":"IF('MEW plant'!#REF!=\"\",\"\",'MEW plant'!#REF!)","v":{"$error":"#REF!"}},{"$f":"IF('MEW plant'!H63=\"\",\"\",'MEW plant'!H63)","v":""},{"$f":"IF('MEW plant'!H66=\"\",\"\",'MEW plant'!H66)","v":""}]
[{"$f":"'MEW plant'!G3","v":"Species (Scientific name)"},{"$f":"'MEW plant'!G4","v":"Lifestage"},{"$f":"'MEW plant'!G5","v":"Exposure duration"},{"$f":"'MEW plant'!G6","v":"Measure of toxicity"},{"$f":"'MEW plant'!G7","v":"Toxicity endpoint"},{"$f":"'MEW plant'!G8","v":"Toxicity value"},{"$f":"'MEW plant'!J2","v":"Taxonomic group"},{"$f":"'MEW plant'!J3","v":"Phylum"},{"$f":"'MEW plant'!J4","v":"Class"},{"$f":"'MEW plant'!J5","v":"Media"},{"$f":"'MEW plant'!J6","v":"Temperature "},{"$f":"'MEW plant'!J7","v":"Acute Or Chronic "},{"$f":"'MEW plant'!J8","v":"PH"},{"$f":"'MEW plant'!J9","v":"Salinity/Conductivity"},{"$f":"'MEW plant'!C4","v":"Citation"},{"$f":"'MEW plant'!G2","v":"Citation No."}]
[{"$f":"'MEW plant'!Q3","v":"Chlorella sp."},{"$f":"'MEW plant'!T3","v":"N.A."},{"$f":"'MEW plant'!W3","v":"3 days"},{"$f":"'MEW plant'!Z3","v":"EC50"},{"$f":"'MEW plant'!AC3","v":"Growth"},{"$f":"IF('MEW plant'!H8=\"\",\"\",'MEW plant'!H8)","v":"0.83 mg/L"},{"$f":"'MEW plant'!AF3","v":"N.A."},{"$f":"'MEW plant'!AI3","v":"Chlorophyta"},{"$f":"'MEW plant'!AL3","v":"Trebouxiophyceae"},{"$f":"'MEW plant'!AO3","v":"Natural and artificial seawater"},{"$f":"'MEW plant'!AR3","v":"N.A."},{"$f":"'MEW plant'!AU3","v":"N.A."},{"$f":"'MEW plant'!AX3","v":"N.A."},{"$f":"'MEW plant'!BA3","v":"30 ppt"},{"$f":"IF('MEW plant'!E4=\"\",\"\",'MEW plant'!E4)","v":"Walsh, G.E., M.J. Yoder, L.L. McLaughlin and E.M. Lores. 1987. Response of marine unicellular algae to brominated organic compounds in six growth media. Ecotoxicology and Environmental Safety 14: 215-222"},{"$f":"IF('MEW plant'!H2=\"\",\"\",'MEW plant'!H2)","v":"291"}]

{"sheet":"MEW nonplant","index":5,"n_rows":84,"n_cols":53,"rows_kept":84,"cut":false,"hidden":false,"merged":[[3,4,7,4],[9,2,9,4],[11,2,13,2],[11,7,13,7],[14,2,16,2],[14,7,16,7],[17,2,19,2],[17,7,19,7],[20,2,21,2],[20,7,21,7],[22,2,24,2],[22,7,24,7],[25,2,27,2],[25,7,27,7],[28,2,30,2],[28,7,30,7],[31,2,33,2],[31,7,33,7],[34,2,36,2],[34,7,36,7],[37,2,39,2],[37,7,39,7],[40,2,42,2],[40,7,42,7],[43,2,45,2],[43,7,45,7],[46,2,48,2],[46,7,48,7],[49,2,51,2],[49,7,51,7],[68,2,71,2],[68,7,71,7],[56,7,58,7],[65,7,67,7],[52,2,54,2],[52,7,54,7],[59,7,61,7],[65,2,67,2],[62,2,64,2],[62,7,64,7]]}
[null,1,"Fill in the blank cells below, based on information provided in the paper being assessed. You can either pick an option from the dropdown list or add the appropriate detail using the 'Add to list' button. ",null,null,{"$f":"IF(BA3=\"\",0,1)","v":1},null,null,null,null,null,null,null,null,"* All the text in RED are used for drop down list ,make changes with caution."]
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[null,null,"Citation",{"$f":"IF(AL3=\"\",0,1)","v":1},"Ebenezer V. and J.S. Ki. 2012. Evaluation of the sub-lethal toxicity of Cu, Pb, bisphenol A and polychlorinated biphenyl to the marine dinoflagellate Cochlodinium polykrikoides. Algae 27: 63-70",{"$f":"IF(H8=\"\",0,1)","v":1},"Lifestage",null,null,"Class",null,null,null,null,"Aedes albopictus",null,null,"1 year old",null,null,"10 day",null,null,"EC10",null,null,"Adult survival",null,null,"Algae",null,null,"Arthropoda",null,null,"\tAscidiacea",null,null,"Artificial seawater",null,null,10,null,null,"25 ± 1",null,null,7.90,null,null,20]
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[null,2,"Select the appropriate answer option to each question. Comments can be added to the cells in column H.",null,null,{"$f":"IF(Z3=\"\",0,1)","v":1},null,null,null,"Salinity/Conductivity",null,null,null,null,"Australian Bass",null,null,"adult",null,null,"15 day",null,null,"LC10",null,null,"Development",null,null,"Fish ",null,null,"Cyanobacteria",null,null,"Bacillariophyceae",null,null,"filtered seawater",null,null,18,null,null,null,null,null,"7.5-8.1",null,null,20.70]
[null,"*","If the selected answer option does not work try clicking on any other cell first and then click back on the answer option again.",null,null,{"$f":"IF(AC3=\"\",0,1)","v":1},null,null,null,null,null,null,null,null,"Chlorella sp.",null,null,"adult",null,null,"15 mins",null,null,"LC50",null,null,"Development",null,null,"Lobster",null,null,"Dinoflagellata",null,null,"Bivalvia",null,null,"Filtered synthetic seawater",null,null,19,null,null,null,null,null,"7.6-8.0",null,null,26]
[null,"No.","Question","Marks Awarded","Answer Options","Option References","Scores","Answers",null,null,null,null,null,null,"Chroococcus minor",null,null,"adult",null,null,"15 minutes",null,null,"LC50",null,null,"Development",null,null,"macroinvertebrate",null,null,"Echinodermata",null,null,"Branchiopoda",null,null,"fresh or artificial seawater",null,null,20,null,null,null,null,null,"7.7-8.1",null,null,30]
[null,null,"Was the duration of the exposure stated (e.g. 48 or 96 h)?",10,null,1,{"$f":"IF(F15=0,0,INDEX($D12:$D13,F12,1))","v":10},"3 days",null,null,null,null,null,null,"Ciona intestinalis",null,null,"Adult",null,null,"16 day",null,null,"LOEC",null,null,"Development rate",null,null,"Macroinvertebrate",null,null,"Euarthropoda",null,null,"Branchiopoda",null,null,"Freshwater",null,null,21,null,null,null,null,null,"7.8-8.2",null,null,30]
[null,1,null,0,null,null,null,null,null,null,null,null,null,null,"Cochlodinium polykrikoides",null,null,"Egg",null,null,"16 day",null,null,"LOEL",null,null,"Development: abnormal development",null,null,"Microalga",null,null,"Mollusca",null,null,"Chlorophyceae",null,null,"marine water",null,null,23.20,null,null,null,null,null,"7.9-8.2",null,null,31]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Corophium volutator",null,null,"embryo",null,null,"17 day",null,null,"LOEL",null,null,"egg extrusion",null,null,"Microalgae",null,null,"Myzozoa",null,null,"Coscinodiscophyceae",null,null,"Marinewater",null,null,24,null,null,null,null,null,"8 ± 0.2",null,null,32]
[null,null,"Was the biological endpoint (e.g., immobilization or population growth) stated and defined (10 marks)? Award 5 marks if the biological endpoint is only stated.",10,null,1,{"$f":"IF(F15=0,0,INDEX($D15:$D17,F15,1))","v":10},"cell counts",null,null,null,null,null,null,"Crassostrea virginica",null,null,"Embryo",null,null,"2 days",null,null,"N.A.",null,null,"embryonic development",null,null,"microinvertebrate",null,null,"N.A.",null,null,"Cyanophyceae",null,null,"N.A.",null,null,25,null,null,null,null,null,"8 ± 0.3",null,null,"150 uS/cm"]
[null,2,null,5,null,null,null,null,null,null,null,null,null,null,"Cyprinidon variegatus",null,null,"embryo",null,null,"20 day",null,null,"NOEC",null,null,"embryonic development",null,null,"Microinvertebrate",null,null,"Ochrophyta",null,null,"Dinophyceae",null,null,"natural and artificial seawater",null,null,25,null,null,null,null,null,"8.1+-0.2",null,null,"18 ppt"]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,"Elasmopus rapax",null,null,"Embryo",null,null,"21 days",null,null,"NOEC",null,null,"embryonic/larval growth",null,null,"N.A.",null,null,"Proteobacteria",null,null,"Gammaproteobacteria",null,null,"natural seawater",null,null,25,null,null,null,null,null,"8.1–8.4",null,null,"20 ppt"]
[null,null,"Was the biological effect stated (e.g. LC or NOEC)?",5,null,1,{"$f":"IF(F18=0,0,INDEX($D18:$D19,F18,1))","v":5},"EC50",null,null,null,null,null,null,"Haliotis diversicolor supertexta",null,null,"embryo (D-veliger)",null,null,"24 day",null,null,"NOEL",null,null,"emyonic development",null,null,"Rotifer",null,null,"Rotifera",null,null,"Gastropoda",null,null,"natural seawater",null,null,25.30,null,null,null,null,null,"8.23±0.01",null,null,"20.3 ± 0.4 ppt"]
[null,3,null,0,null,null,null,null,null,null,null,null,null,null,"Hemicentrotus pulcherrimus",null,null,"female mature",null,null,"24 dyas",null,null,"NOEL",null,null,"Female mortality",null,null,"Sea urchin",null,null,"Tracheophyta",null,null,"Haliotidae",null,null,"Natural seawater",null,null,25.60,null,null,null,null,null,"N.A.",null,null,"20.4-22.8"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Homarus americanus",null,null,"female stage 1 juvenile",null,null,"24 hrs",null,null,null,null,null,"gill sodium ion activity",null,null,"Dinoflagellate",null,null,"Trbouxiophyceae",null,null,"Malacostraca",null,null,"not stated",null,null,25.60,null,null,null,null,null,"not stated",null,null,"20.4-22.8‰"]
[null,4,"Was the biological effect quantified (e.g. 50% effect, 25% effect)? \nNote: The effect for NOEC and LOEC data must be quantified.",5,null,1,{"$f":"IF(F21=0,0,INDEX($D21:$D22,F21,1))","v":5},0.50,null,null,null,null,null,null,"Hydroides elegans",null,null,"Fresh culture <10 days",null,null,"25 day",null,null,null,null,null,"Growth",null,null,null,null,null,"Miozoa",null,null,"Malacostraca",null,null,"Not stated",null,null,26.50,null,null,null,null,null,"Not stated",null,null,"25 o/00 "]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,"Ilyanassa obsoleta",null,null,"Gravid female",null,null,"28 day",null,null,null,null,null,"Growth - body length and width",null,null,null,null,null,null,null,null,"Maxillopoda",null,null,"Salt water algal assay medium ",null,null,27,null,null,null,null,null,"Not stated",null,null,"25 ppt"]
[null,5,"Were appropriate controls (e.g. a no-toxicant control and/or solvent control) used?",5,null,1,{"$f":"IF(F23=0,0,INDEX($D23:$D24,F23,1))","v":5},"Filtered seawater",null,null,null,null,null,null,"Menidia menidia",null,null,"II-III instar larvae",null,null,"3 days",null,null,null,null,null,"Growth - development",null,null,null,null,null,null,null,null,"Maxillopoda",null,null,"Saltwater algal assay medium",null,null,27,null,null,null,null,null,"Not stated",null,null,"28-32 %"]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,"Mercenaria mercenaria",null,null,"juvenile",null,null,"30 day",null,null,null,null,null,"Growth - development",null,null,null,null,null,null,null,null,"Mediophyceae",null,null,"sand filtered seawater",null,null,27,null,null,null,null,null,"Not stated",null,null,"30 o/00"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Mysidopsis bahia",null,null,"juvenile",null,null,"32d (3 brood)",null,null,null,null,null,"Growth: Body length",null,null,null,null,null,null,null,null,"N.A.",null,null,"seawater",null,null,35,null,null,null,null,null,"PH11",null,null,"30 ppt"]
[null,6,"Was each control and contaminant concentration at least duplicated?",5,null,1,{"$f":"IF(F26=0,0,INDEX($D26:$D27,F26,1))","v":5},"Yes",null,null,null,null,null,null,"Mytilus edulis",null,null,"juvenile (212-350um)",null,null,"4 days",null,null,null,null,null,"Growth: length",null,null,null,null,null,null,null,null,"Trebouxiophyceae",null,null,"seawater",null,null,40,null,null,null,null,null,"PH7.0",null,null,"30-32 PSU"]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,"N.A.",null,null,"Larvae",null,null,"45 day",null,null,null,null,null,"Growth: Length",null,null,null,null,null,null,null,null,"Dinophyceae",null,null,"Seawater and solvent",null,null,"15°C",null,null,null,null,null,null,null,null,"32 g/L"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Oryzias melastigma",null,null,"larvae",null,null,"48 hour",null,null,null,null,null,"Growth: Length (mm)",null,null,null,null,null,null,null,null,null,null,null,"seawater UV treated natural",null,null,"16-18",null,null,null,null,null,null,null,null,"32 o/00"]
[null,7,"Were test acceptability criteria stated (e.g. mortality in controls must not exceed a certain percentage) (5 marks)?\nOR Were test acceptability criteria inferred (e.g. test method used [USEPA, OECD, ASTM etc.]) (award 2 marks). \nNote: Data that fail the acceptability criteria are automatically deemed to be of unacceptable quality and must not be used. ",5,null,2,{"$f":"IF(F29=0,0,INDEX($D29:$D31,F29,1))","v":2},"OECD guidelines ",null,null,null,null,null,null,"Palaemonetes pugio",null,null,"larvae",null,null,"48hr",null,null,null,null,null,"Growth: Shell area",null,null,null,null,null,null,null,null,null,null,null,"Seawater with added DOM",null,null,"18-20",null,null,null,null,null,null,null,null,"33 ± 0.5"]
[null,null,null,2,null,null,null,null,null,null,null,null,null,null,"Palaemonetes pugio",null,null,"Larvae",null,null,"48hr",null,null,null,null,null,"Growth: Shell length",null,null,null,null,null,null,null,null,null,null,null,"unfiltered seawater",null,null,"18-22",null,null,null,null,null,null,null,null,"35.1±0.64"]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,"Paracentrotus lividus",null,null,"larvae",null,null,"5 day",null,null,null,null,null,"Growth: weight",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"19.5-20.5",null,null,null,null,null,null,null,null,"5000 uS/cm"]
[null,8,"Were the characteristics of the test organism (e.g. length, mass, age) stated?",5,null,1,{"$f":"IF(F32=0,0,INDEX($D32:$D34,F32,1))","v":5},"Cell culture",null,null,null,null,null,null,"Paracentrotus lividus",null,null,"Larvae (Naupliar <24 hours old)",null,null,"5 days",null,null,null,null,null,"Growth: Weight",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"19-21",null,null,null,null,null,null,null,null,"N.A."]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,"Philodina acuticornis odiosa",null,null,"Larvae (Naupliar)",null,null,"50 day",null,null,null,null,null,"Growth: Wet weight",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"20 ± 1",null,null,null,null,null,null,null,null,"not stated"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Photobacterium phosphoreum",null,null,"larval life cycle",null,null,"7 days",null,null,null,null,null,"Hatch time",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"20±2",null,null,null,null,null,null,null,null,"Not stated"]
[null,9,"Was the type of test media used stated?",5,null,1,{"$f":"IF(F35=0,0,INDEX($D35:$D37,F35,1))","v":5},"Filtered seawater supplemented with macronutrients, vitamins and trace metals",null,null,null,null,null,null,"Prorocentrum minimum",null,null,"Life cycle",null,null,"80 days",null,null,null,null,null,"immobilisation",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"21-23"]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,"Psammechinus miliaris",null,null,"Life cycle",null,null,"96 hr",null,null,null,null,null,"Immobilisation",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"22-26"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Salmo salar",null,null,"male mature",null,null,"96hr",null,null,null,null,null,"larval development",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"23.2 ± 0.4°C"]
[null,null,"Was the type of exposure (e.g. static, flow through) stated? ",4,null,1,{"$f":"IF(F38=0,0,INDEX($D38:$D40,F38,1))","v":4},"static",null,null,null,null,null,null,"Salmo salar",null,null,"male stage 1 juvenile",null,null,"96hr",null,null,null,null,null,"larval growth",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"24-26"]
[null,10,null,0,null,null,null,null,null,null,null,null,null,null,"Sammechinus miliaris",null,null,"mature",null,null,"96hr",null,null,null,null,null,"lipid content",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"25 ± 1"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Selenastrum capricornutum",null,null,"N.A.",null,null,"N.A.",null,null,null,null,null,"loss of righting ability",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"25 ± 1"]
[null,null,"Were the contaminant concentrations measured at the beginning and end of the exposure (4 marks)? Award 2 marks if they were measured only once during the test.\nNote: If the concentrations were not measured then automatically the data cannot be high quality. ",4,null,3,{"$f":"IF(F41=0,0,INDEX($D41:$D43,F41,1))","v":0},"Not stated",null,null,null,null,null,null,"Skeletonema costatum",null,null,"Nauplii (larvae)",null,null,null,null,null,null,null,null,"Male development",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"25 ± 1°C"]
[null,11,null,2,null,null,null,null,null,null,null,null,null,null,"Strongylocentrotus purpuratus",null,null,"Not stated",null,null,null,null,null,null,null,null,"Male mortality",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"25 °C"]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,"Tigriopus japonicus",null,null,"pre-smolt",null,null,null,null,null,null,null,null,"Mortality",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"25°C"]
[null,null,"Were parallel reference toxicant toxicity tests conducted?",4,null,2,{"$f":"IF(F44=0,0,INDEX($D44:$D46,F44,1))","v":0},"Not stated",null,null,null,null,null,null,"Tigriopus japonicus",null,null,"pre-smolts",null,null,null,null,null,null,null,null,"Mortality",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"27-29"]
[null,12,null,0,null,null,null,null,null,null,null,null,null,null,null,null,null,"Stage 1 juvenile",null,null,null,null,null,null,null,null,"N.A.",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"28.5-31.1"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"stage 1 juvenile ",null,null,null,null,null,null,null,null,"reduced swimming",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"28.5-31.1°C"]
[null,null,"Was there a concentration–response relationship either observable or stated?",4,null,1,{"$f":"IF(F47=0,0,INDEX($D47:$D49,F47,1))","v":4},"Table 2",null,null,null,null,null,null,null,null,null,"stage 6 larvae",null,null,null,null,null,null,null,null,"Relative growth rate",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"N.A."]
[null,13,null,0,null,null,null,null,null,null,null,null,null,null,null,null,null,"stage VI embryo",null,null,null,null,null,null,null,null,"Reproduction",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Not stated"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Stage-I Juveniles",null,null,null,null,null,null,null,null,"Reproduction success",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"sand filtered seawater"]
[null,null,"Was an appropriate statistical method or model used to determine the toxicity?\nNote: They should be accepted by a recognised national or international regulatory body (e.g. USEPA, OECD, ASTM). ",4,null,1,{"$f":"IF(F50=0,0,INDEX($D50:$D52,F50,1))","v":4},null,null,null,null,null,null,null,null,null,null,"Trochophore larvae (< 24 h old)",null,null,null,null,null,null,null,null,"Reproduction: Fercundity",null,null,null,null,null,null,null,null,null,null,null,null,null,null,"unfiltered seawater"]
[null,14,null,0,null,null,null,null,null,null,null,null,null,null,null,null,null,"Exponential growth phase",null,null,null,null,null,null,null,null,"Reproduction: Fertility"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Reproduction: Viable offspring production"]
[null,15,"For LC/EC/BEC data was an estimate of variability provided? \nOR \nFor NO EC/LOEC data was the significance level 0.05 or less?  \n\n",4,null,1,{"$f":"IF(F53=0,0,INDEX($D53:$D55,F53,1))","v":4},null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Reproductive success"]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Reproductive success"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Reproductive success: Mean % brood sac extrusion"]
[null,16,"Were the following parameters measured and stated? (3 marks if measured and stated, 1 mark if just measured).",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"retraction"]
[null,null,null,3,null,3,{"$f":"IF(F57=0,0,INDEX($D57:$D59,F57,1))","v":0},null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Sex ratio"]
[null,16.10,"Conductivity/Salinity",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Survival"]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Survival"]
[null,null,null,3,null,3,{"$f":"IF(F60=0,0,INDEX($D60:$D62,F60,1))","v":0},null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Survival"]
[null,16.20,"Dissolved Oxygen",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Survival"]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Survival"]
[null,null,"pH",3,null,3,{"$f":"IF(F63=0,0,INDEX(D63:D65,F63,1))","v":0},null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Survival"]
[null,16.30,null,1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Survival to adult"]
[null,null,null,0,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Survival: Persistence of toxicity"]
[null,null,"Was the temperature measured and stated (3 marks)? Award 1 mark if the temperature was measured but not stated or if only the temperature settings of the room or chamber are stated.\n\n",3,null,1,{"$f":"IF(F66=0,0,INDEX(D66:D68,F66,1))","v":3},"20oC",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Viable offspring"]
[null,17,null,1]
[null,null,null,0]
[null,null,"Were test solutions, blanks and/or controls tested for contamination OR were analytical reagent grade chemicals used or the highest possible purity chemicals used for the experiment? (3 marks).",3,null,1,{"$f":"IF(F69=0,0,INDEX($D69:$D70,F69,1))","v":3},"Analytica grade reagent; Cat no. A133027; Sigma-Aldrich"]
[null,18,null,0]
[]
[null,null,null,null,null,null,null,null,{"$f":"(COUNTIF(F12:F70,\"=0\"))+COUNTIF(F1:F10,\"=0\")+COUNTIF(D2:D7,\"=0\")","v":0}]
[]
[]
[null,null,"Total score",null,null,null,{"$f":"IF(SUM(G12:G69)=0,\"\",SUM(G12:G69))","v":74}]
[null,null,"Total Max. possible score for the various types of data and contaminants ",null,{"$f":"D12+D15+D18+D21+D23+D26+D29+D32+D35+D38+D41+D44+D47+D50+D53+D57+D60+D66+D69+D63","v":94}]
[null,null,"Quality Score",null,{"$f":"\"= [Total score / Total possible score] * 100 = \"","v":"= [Total score / Total possible score] * 100 = "},null,{"$f":"IF(ISERROR(G75/E76),#N/A,G75/E76)","v":0.78723404255319152},{"$f":"IF(F41=3,\"The highest possible grade for this datum is acceptable.\",\"\")","v":"The highest possible grade for this datum is acceptable."}]
[]
[null,null,"H = high quality                           Quality score ≥ 80%"]
[null,null,"A = acceptable quality         > 50% Quality score < 80%  "]
[null,null,"U = unacceptable quality              Quality score ≤ 50%"]
[]
[3,null,"Click the 'Save & Update' button to save and export the answers to the 'All results' worksheet. "]
[null,null,"Select the 'Reset Answers' button if you wish to clear all answers."]

{"sheet":"MEW nonplant_WS","index":6,"n_rows":128,"n_cols":24,"rows_kept":128,"cut":false,"hidden":false,"merged":[]}
[]
["Question No.",1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16.10,16.20,16.30,17,18,"Total Score","Quality Score"]
["Short Questions","Duration of the exposure ","Biological endpoint","Biological effect stated or not","Biological effect quantified or not","Appropriate controls","Control & contaminant concentration","Test acceptability criteria","Characteristics of the test organism"," Type of test media","Type of exposure","Contaminant concentrations","Parallel reference toxicant toxicity tests","Concentration–response relationship","Determine the toxicity","NOEC/LOEC or LC/EC/BEC","Conductivity/Salinity","Dissolved Oxygen","PH","Temperature","Grade or purity"]
["Marks Awarded ","10 or 0","10,5 or 0","5 or 0 ","5 or 0 ","5 or 0 ","5 or 0 ","5 or 0 ","5 or 0 ","5 or 0 ","4 or 0","4 or 2 or 0","4 or 2","4 or 2","4 or 2","4 or 2","3 or 1 or 0","3 or 1 or 0","3 or 1 or 0","3 or 0","3 or 0 "]
["Max. Possible Score",10,10,5,5,5,5,5,5,5,4,4,4,4,4,4,3,3,3,3,3,{"$f":"SUM(B5:U5)","v":94}]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","269-1"]
["Scores",10,10,5,5,5,5,0,5,5,4,0,0,0,4,4,0,0,0,3,3,68,0.72340425531914898,"The highest possible grade for this datum is acceptable."]
["Answers","80 days","growth - diameter","LOEC","NOEC","Yes - seawater + DMSO","Yes","","Yes - juveniles immediately after metamorphosis","Yes - seawater","static renewal","No - Not stated","No - Not stated","Only one concentration tested","Yes","Yes","","","","18oC","BPA"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","270-3"]
["Scores",10,10,5,5,5,5,0,5,5,4,0,0,0,4,4,3,0,0,3,3,71,0.75531914893617025,"The highest possible grade for this datum is acceptable."]
["Answers","5 days","inhibition of development","EC10","Inhibition of larval development - EC10","Yes - artificial seawater control","Yes - 12 dups for the control and 4 dups for each test concentration","","Yes - age","Yes - artificial seawater","static - renewal","No","No - Not stated","No","Yes","Yes","18 ppt o/oo","","","20+/-0.5oC","BPA (CAS 80-05-7) >97% purity"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","270-3"]
["Scores",10,10,5,5,5,5,0,5,5,4,0,0,0,4,4,3,0,0,3,3,71,0.75531914893617025,"The highest possible grade for this datum is acceptable."]
["Answers","5 days","inhibition of development","EC10","Inhibition of larval development - EC10","Yes - artificial seawater control","Yes - 12 dups for the control and 4 dups for each test concentration","","Yes - age","Yes - artificial seawater","static - renewal","No","No - Not stated","No","Yes","Yes","18 ppt o/oo","","","20+/-0.5oC","BPA (CAS 80-05-7) >97% purity"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","272-1"]
["Scores",10,10,5,5,5,5,0,5,5,4,0,0,4,4,4,0,0,0,3,0,69,0.73404255319148937,"The highest possible grade for this datum is acceptable."]
["Answers","4 days","Larval development","EC50","EC50","Yes - seawater and solvent controls","Yes - triplicate","-","Yes - larvae","Yes - seawater and solvent","Static","No - not stated","No - not stated","Yes Figure 3","Yes","Yes","-","-","-","17oC","-"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","281-1"]
["Scores",10,10,5,5,5,5,2,5,5,4,0,0,0,4,4,3,0,0,3,0,70,0.74468085106382975,"The highest possible grade for this datum is acceptable."]
["Answers","4 days","Survival - no visible movement or response to stimuli","LC50","LC50","Yes - artificial seawater control and solvent control","Based on USEPA procedures so assume yes","Yes - as per EPA standards. Equal to or greater than 90% survival in the controls.","Yes - 24 hr old larvae","Yes saewater and solvent","Static renewal (daily)","No - not stated","No - not stated","No - not stated","Yes","Yes","25 o/00","","","25+/-1oC",""]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","282-1"]
["Scores",10,10,5,5,5,5,0,5,5,4,0,0,0,4,4,3,0,0,3,0,68,0.72340425531914898,"The highest possible grade for this datum is acceptable."]
["Answers","14 days","Growth - body length and width - using two dimensional measuring software","LOEC","LOEC","Yes seawater and solvent control","Yes three replicates","-","Yes - age 2 days post hatch","Yes - age 2 days post hatch","Static renewal (daily)","No - not stated","No - not stated","No only one exposure concentration","Yes","Yes","30 o/00","","","28+/-1oC",""]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","287-3"]
["Scores",10,10,5,5,5,5,2,5,5,4,4,0,4,4,4,3,3,3,3,3,87,0.92553191489361697,""]
["Answers","4 days","Survival","LC50","LC50","Seawater (Cape Cod Canal)","Assume yes as ASTM procedures followed","ASTM procedures","Lab culture","Seawater (Cape Cod Canal)","Flow-through","Measured using reverse-phase liquid chromatography","No - not stated","Yes Table 8","Yes","Yes","20 ppt","Table 2","7.5-8.1","25+/-1oC","Yes -99.93% "]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","287-4"]
["Scores",10,10,5,5,5,5,5,5,5,4,4,0,4,4,4,3,3,3,3,3,90,0.95744680851063835,""]
["Answers","4 days","Survival","LC50","LC50","Seawater (Cape Cod Canal)","Assume yes as ASTM procedures followed","ASTM procedures","Lab culture","Seawater (Cape Cod Canal)","Flow-through","Table 9","No - not stated","Yes - Table 9","Yes","Yes","20 ppt","Table 2","7.9-8.2","22+/-1oC","Yes - 99.93%"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","741-1"]
["Scores",10,10,5,5,5,5,5,5,5,4,0,0,0,4,4,0,3,3,3,0,76,0.80851063829787229,"The highest possible grade for this datum is acceptable."]
["Answers","1 day","Survival","EC50","EC50","Artificial Seawater","Yes","Assume so as using a modified ARS test procedure","Yes - first instar nauplii","Artificial Seawater","Static","No - not stated","No - not stated","","Yes","Yes","","8.5 +/- 0.5 mg/L","7.8 +/ -0.2","25oC",""]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","743-1"]
["Scores",10,10,5,5,5,5,2,5,5,4,0,0,4,4,4,0,0,0,3,0,71,0.75531914893617025,"The highest possible grade for this datum is acceptable."]
["Answers","3 days","Growth inhibition","EC50","EC50","Seawater","Yes duplicated","OECD guidelines","Yes - initial cell density","Seawater","Static","No - not stated","No - not stated","Yes - Figure 3","Yes","Yes","","","","20oC",""]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","744-1"]
["Scores",10,10,5,0,5,5,0,5,5,4,0,0,4,4,4,3,3,3,3,3,76,0.80851063829787229,"The highest possible grade for this datum is acceptable."]
["Answers","5 days","evelopment - metamorphosis","NOEC","","sand filtered seawater and acetone solvent","Yes - three reps","","Yes - age post fertilization","sand filtered seawater","Static","No - not stated","No - not stated","Yes - Figure 2","Yes","Yes","30 +/- 2 %","> 6.0 mg/L","8.0 +/- 0.2","24 +/- 2 oC","98.0 % BPA"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","745-1"]
["Scores",10,10,5,0,5,5,0,5,5,4,0,0,4,4,4,3,0,0,3,3,70,0.74468085106382975,"The highest possible grade for this datum is acceptable."]
["Answers","21 days","Nauplii development - number of days from birth to days reach copepodid stage. ","NOEC","","Yes seawater and a solvent control","Yes - triplicate","","Yes - age","Seawater","Static","No - not stated","No - not stated","Yes Table 2","Yes","Yes","25 ppt","","","25oC","BPA 98-99% purity"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","745-1"]
["Scores",10,10,0,0,5,5,0,5,5,4,0,0,4,4,4,3,0,0,3,3,65,0.69148936170212771,"The highest possible grade for this datum is acceptable."]
["Answers","21 days","Nauplii development - number of days from birth to days reach copepodid stage. ","NOEC","","Yes seawater and a solvent control","Yes - triplicate","","Yes - age","Seawater","Static","No - not stated","No - not stated","Yes Table 2","Yes","Yes","25 ppt","","","25oC","BPA 98-99% purity"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","744-1"]
["Scores",10,10,0,0,5,5,0,5,5,4,0,0,4,4,4,3,3,3,3,3,71,0.75531914893617025,"The highest possible grade for this datum is acceptable."]
["Answers","5 days","Development - metamorphosis","No - NOEC","No - NOEC","Sand filtered seawater and acetone solvent","Yes three reps","","Yes - age post fertilization","sand filtered seawater","Static","No - not stated","No - not stated","Yes - Figure 2","Yes","Yes","30 +/- 2 %","> 6.0 mg/L","8.0 +/- 0.2","24 +/- 2 oC","98.0 % BPA"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","271-1"]
["Scores",10,10,5,5,5,5,2,5,5,4,0,0,4,4,4,3,3,3,3,3,83,0.88297872340425532,"The highest possible grade for this datum is acceptable."]
["Answers","4 days","Survival","NOEC","NOEC - defined","Yes - solvent control with seawater","Yes - triplicate","Standard static toxicity tests","Yes - adults","Yes - seawater UV treated natural","Static","No - not stated","No - not stated","Yes Figure 1","Yes","Yes","32 o/00","5.24 mg/L",7.90,"20 +/- 1 oC","BPA 99.9% purity"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","280-1"]
["Scores",10,10,5,5,5,5,0,5,5,4,0,0,4,4,4,3,0,0,3,0,72,0.76595744680851063,"The highest possible grade for this datum is acceptable."]
["Answers","25 days","Delayed development - moulting","LOEC","LOEC","Yes - unfiltered seawater","Yes","","Yes - larvae","Yes - unfiltered seawater","Flow through","No - not stated","No - not stated","Yes Figure 1","Yes","Yes","32 g/L","","","16-18 oC",""]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","268-1"]
["Scores",10,10,5,5,5,5,5,5,5,4,4,0,0,4,4,3,0,0,3,3,80,0.85106382978723405,""]
["Answers","7 days","Reproduction - Hatching Success","NOEC","NOEC","Yes - solvent control (DMSO)","Yes","Yes described in Section 2.3. 90% fertilization success. Plus Environment Canada and EPA methodology","Yes - fertilized eggs","FSW or ASW - fresh or artificial seawater","Static","Yes LC-MS","No - not stated","No","Yes","Yes","31 +/- 1 PSU (practical salinity unit)","","","19 +/- 1 oC","TBBPA (tetrabromobisphenol A: CAS 79-94-7 purity 97%)"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3501-1"]
["Scores",10,5,5,5,5,5,2,5,5,4,0,4,4,4,4,1,0,0,1,3,72,0.76595744680851063,"The highest possible grade for this datum is acceptable."]
["Answers","72-h","Larval malformation of the skeleton\\","Table V; LC/EC","Table V; effect quantified at different % values.","Untreated negative control\nCdCL2 positive control \nDMSO solvent control ","3x positive control \nall treatments were tested as six replicates in six-well plates","The use of sea urchin embryos and gametes in testing the developmental, reproductive, and cytogenetic effects of chemicals and complex mixtures has been successfully\ndeveloped by a number of laboratories worldwide (Kobayashi, 1984, 1990; Pagano et al., 1986, Arslan et al., 2007, Arslan and Parlak, 2007).","Embryos","Filtered sea water ","Static; well plates","No discussion of nominal vs. measured concentrations. ","CdCL2 positive control ","Observable, but weak. Table IV shows a does response for death for treatmetn 3.5 to 800, and 2300 to 3500, but does not include 1000 and 1500. ","EPA Probit Analysis Program calaculated LC/EC Values using student's t-tests ","Table V","35 PSU","","","18 ±2 oC","Analytical grade BPA was purchased from Aldrich, Germany"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3501-2"]
["Scores",10,5,5,5,5,5,2,5,5,4,0,4,4,4,4,1,0,0,1,3,72,0.76595744680851063,"The highest possible grade for this datum is acceptable."]
["Answers","72-h","Larval malformation of the skeleton\\","Table V; LC/EC","Table V; effect quantified at different % values.","Untreated negative control\nCdCL2 positive control \nDMSO solvent control ","3x positive control \nall treatments were tested as six replicates in six-well plates","The use of sea urchin embryos and gametes in testing the developmental, reproductive, and cytogenetic effects of chemicals and complex mixtures has been successfully\ndeveloped by a number of laboratories worldwide (Kobayashi, 1984, 1990; Pagano et al., 1986, Arslan et al., 2007, Arslan and Parlak, 2007).","Embryos","Filtered sea water ","Static; well plates","No discussion of nominal vs. measured concentrations. ","CdCL2 positive control ","Observable, but weak. Table IV shows a does response for death for treatmetn 3.5 to 800, and 2300 to 3500, but does not include 1000 and 1500. ","EPA Probit Analysis Program calaculated LC/EC Values using student's t-tests ","Table V","35 PSU","","","18 ±2 oC","Analytical grade BPA was purchased from Aldrich, Germany"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3501-3"]
["Scores",10,5,5,5,5,5,2,5,5,4,0,4,4,4,4,1,0,0,1,3,72,0.76595744680851063,"The highest possible grade for this datum is acceptable."]
["Answers","72-h","Larval malformation of the skeleton\\","Table V; LC/EC","Table V; effect quantified at different % values.","Untreated negative control\nCdCL2 positive control \nDMSO solvent control ","3x positive control \nall treatments were tested as six replicates in six-well plates","The use of sea urchin embryos and gametes in testing the developmental, reproductive, and cytogenetic effects of chemicals and complex mixtures has been successfully\ndeveloped by a number of laboratories worldwide (Kobayashi, 1984, 1990; Pagano et al., 1986, Arslan et al., 2007, Arslan and Parlak, 2007).","Embryos","Filtered sea water ","Static; well plates","No discussion of nominal vs. measured concentrations. ","CdCL2 positive control ","Observable, but weak. Table IV shows a does response for death for treatmetn 3.5 to 800, and 2300 to 3500, but does not include 1000 and 1500. ","EPA Probit Analysis Program calaculated LC/EC Values using student's t-tests ","Table V","35 PSU","","","18 ±2 oC","Analytical grade BPA was purchased from Aldrich, Germany"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3501-4"]
["Scores",10,5,5,0,5,5,2,5,5,4,0,4,0,4,4,1,0,0,1,3,63,0.67021276595744683,"The highest possible grade for this datum is acceptable."]
["Answers","72-h","Larval malformation as skeleton deformitites at the pluteus stage. ","NOEC","","Untreated negative control\nCdCL2 positive control \nDMSO solvent control ","3x positive control \nall treatments were tested as six replicates in six-well plates","The use of sea urchin embryos and gametes in testing the developmental, reproductive, and cytogenetic effects of chemicals and complex mixtures has been successfully\ndeveloped by a number of laboratories worldwide (Kobayashi, 1984, 1990; Pagano et al., 1986, Arslan et al., 2007, Arslan and Parlak, 2007).","Embryos","Filtered sea water ","Static; well plates","No discussion of nominal vs. measured concentrations. ","CdCL2 positive control ","Low concerntrations of BPA appear to show a does response however concentrations of 2300 and 3500 ug/L did not result in larval malformation. ","EPA Probit Analysis Program calaculated LC/EC Values using student's t-tests ","Table V","35 PSU","","","18 ±2 oC","Analytical grade BPA was purchased from Aldrich, Germany"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3501-5"]
["Scores",10,5,5,0,5,5,2,5,5,4,0,4,0,4,4,1,0,0,1,3,63,0.67021276595744683,"The highest possible grade for this datum is acceptable."]
["Answers","72-h","Larval malformation as skeleton deformitites at the pluteus stage. ","NOEC","","Untreated negative control\nCdCL2 positive control \nDMSO solvent control ","3x positive control \nall treatments were tested as six replicates in six-well plates","The use of sea urchin embryos and gametes in testing the developmental, reproductive, and cytogenetic effects of chemicals and complex mixtures has been successfully\ndeveloped by a number of laboratories worldwide (Kobayashi, 1984, 1990; Pagano et al., 1986, Arslan et al., 2007, Arslan and Parlak, 2007).","Embryos","Filtered sea water ","Static; well plates","No discussion of nominal vs. measured concentrations. ","CdCL2 positive control ","Low concerntrations of BPA appear to show a does response however concentrations of 2300 and 3500 ug/L did not result in larval malformation. ","EPA Probit Analysis Program calaculated LC/EC Values using student's t-tests ","Table V","35 PSU","","","18 ±2 oC","Analytical grade BPA was purchased from Aldrich, Germany"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3502-1"]
["Scores",10,10,5,5,5,5,2,5,5,4,2,0,4,4,4,3,3,3,3,3,85,0.9042553191489362,""]
["Answers","96 hours","% of fully metamorphosed larvae. Full metamorphosis was defined as the appearance of the peristomial shell.","HC/EC5",5,"solvent control","3 replicates were prepared for each test concentration and the solvent control ","No internationally acceptable accetability criteria avaliable for this test. Professional judgement was used to assess the acceptablility of the data. ","Eggs released from 20 femals and sperms released from 10 males were mixed for 10 minutes and washed three times with seawater to remove excess sperms. ","Seawater filtered throguh a Whatman GF/B filtration membrane (1um) prior to use. ","Static, bwith distilled milli-Q water added regularly to maintain a stable salinity. ","Measured immediately after spiking ","","Figure 2","Figure 2","Figure 2","30 ±1%","6.0 ±0.2 mg/L","8.1 ± 0.1","25 ±1oC",">99% purity "]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3502-2"]
["Scores",10,10,5,5,5,5,2,5,5,4,2,0,4,4,4,3,3,3,3,3,85,0.9042553191489362,""]
["Answers","96 hours","% of fully metamorphosed larvae. Full metamorphosis was defined as the appearance of the peristomial shell.","HC/EC5",5,"solvent control + a second test where the substrate (glass plate and diatoms) had not been subject to exposure to BPA prior to adding it to the test. ","3 replicates were prepared for each test concentration and the solvent control ","No internationally acceptable accetability criteria avaliable for this test. Professional judgement was used to assess the acceptablility of the data. ","Eggs released from 20 femals and sperms released from 10 males were mixed for 10 minutes and washed three times with seawater to remove excess sperms. ","Seawater filtered throguh a Whatman GF/B filtration membrane (1um) prior to use. ","Static, bwith distilled milli-Q water added regularly to maintain a stable salinity. ","Measured immediately after spiking ","","Figure 2","Figure 2","Figure 2","30 ±1%","6.0 ±0.2 mg/L","8.1 ± 0.1","25 ±1oC",">99% purity "]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3502-3"]
["Scores",10,10,5,5,5,5,2,5,5,4,2,0,4,4,4,3,3,3,3,3,85,0.9042553191489362,""]
["Answers","96 hours","% of fully metamorphosed larvae. Full metamorphosis was defined as the appearance of the peristomial shell.","EC50",50,"solvent control + a second test where the substrate (glass plate and diatoms) had not been subject to exposure to BPA prior to adding it to the test. ","3 replicates were prepared for each test concentration and the solvent control ","No internationally acceptable accetability criteria avaliable for this test. Professional judgement was used to assess the acceptablility of the data. ","Eggs released from 20 femals and sperms released from 10 males were mixed for 10 minutes and washed three times with seawater to remove excess sperms. ","Seawater filtered throguh a Whatman GF/B filtration membrane (1um) prior to use. ","Static, bwith distilled milli-Q water added regularly to maintain a stable salinity. ","Measured immediately after spiking ","","Figure 2","Figure 2","Figure 2","30 ±1%","6.0 ±0.2 mg/L","8.1 ± 0.1","25 ±1oC",">99% purity "]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3502-4"]
["Scores",10,10,5,5,5,5,2,5,5,4,2,0,4,4,4,3,3,3,3,3,85,0.9042553191489362,""]
["Answers","96 hours","% of fully metamorphosed larvae. Full metamorphosis was defined as the appearance of the peristomial shell.","EC50",50,"solvent control","3 replicates were prepared for each test concentration and the solvent control ","No internationally acceptable accetability criteria avaliable for this test. Professional judgement was used to assess the acceptablility of the data. ","Eggs released from 20 femals and sperms released from 10 males were mixed for 10 minutes and washed three times with seawater to remove excess sperms. ","Seawater filtered throguh a Whatman GF/B filtration membrane (1um) prior to use. ","Static, bwith distilled milli-Q water added regularly to maintain a stable salinity. ","Measured immediately after spiking ","","Figure 2","Figure 2","Figure 2","30 ±1%","6.0 ±0.2 mg/L","8.1 ± 0.1","25 ±1oC",">99% purity "]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3502-5"]
["Scores",10,10,5,5,5,5,2,5,5,4,2,0,4,4,4,3,3,3,3,3,85,0.9042553191489362,""]
["Answers","12 hours","% of embryos normally develping (without skeleton malformations) to the trochopore stage","HC/EC5",5,"solvent control","3 replicates were prepared for each test concentration and the solvent control ","No internationally acceptable accetability criteria avaliable for this test. Professional judgement was used to assess the acceptablility of the data. ","Eggs released from 20 femals and sperms released from 10 males were mixed for 10 minutes and washed three times with seawater to remove excess sperms. ","Seawater filtered throguh a Whatman GF/B filtration membrane (1um) prior to use. ","Static, bwith distilled milli-Q water added regularly to maintain a stable salinity. ","Measured immediately after spiking ","","Figure 2","Figure 2","Figure 2","30 ±1%","6.0 ±0.2 mg/L","8.1 ± 0.1","25 ±1oC",">99% purity "]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3502-6"]
["Scores",10,10,5,5,5,5,2,5,5,4,2,0,4,4,4,3,3,3,3,3,85,0.9042553191489362,""]
["Answers","12 hours","% of embryos normally develping (without skeleton malformations) to the trochopore stage","EC50",50,"solvent control","3 replicates were prepared for each test concentration and the solvent control ","No internationally acceptable accetability criteria avaliable for this test. Professional judgement was used to assess the acceptablility of the data. ","Eggs released from 20 femals and sperms released from 10 males were mixed for 10 minutes and washed three times with seawater to remove excess sperms. ","Seawater filtered throguh a Whatman GF/B filtration membrane (1um) prior to use. ","Static, bwith distilled milli-Q water added regularly to maintain a stable salinity. ","Measured immediately after spiking ","","Figure 2","Figure 2","Figure 2","30 ±1%","6.0 ±0.2 mg/L","8.1 ± 0.1","25 ±1oC",">99% purity "]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3503-1"]
["Scores",10,10,5,5,5,5,0,5,5,4,0,0,4,0,4,0,0,0,1,0,63,0.67021276595744683,"The highest possible grade for this datum is acceptable."]
["Answers","30 minutes ","development: the point at which only 50% of embryoes are sucessfully finishing the fist cell division ","EC",50,"DMSO ",9,"Test does not have standard international acceptabliity critiera. ","Fertilised embryos (minimum >90% fertilisation per batch)","0.2 µM filtered seawater ","Flow through ","Nominal ","","Figure 1","Unspecified. ","Figure 1","","","","15 ± 2oC","test subjestance obtianed from Acros Organiscs. No discussion provided regarding % purity or grade of chemical. "]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","3504-1"]
["Scores",10,10,5,5,5,5,2,5,5,4,0,4,4,4,4,0,0,0,1,0,73,0.77659574468085102,"The highest possible grade for this datum is acceptable."]
["Answers","Incubated for 15 minutes","Fertilisation success was determined using an inverted microscope and was defined as elevation of the fertilization membrane observed at 100x magnification. ","\"no effects were found\"","\"no effects were found\"","non toxicant control ","four replicates per treatment ","","egg","Seawater","static - 24 well microplate","","","Figure 1c. Poor does response. ","","p<0.05","","","","18oC","Not stated. "]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","268-2"]
["Scores",10,10,5,5,5,5,5,5,5,4,2,0,0,4,4,3,3,3,3,3,84,0.8936170212765957,""]
["Answers","7 days","Larval development; presece of short or abnormal arms and edema ","NOEC","NOEC","Yes - solvent control (DMSO)","Yes","Yes described in Section 2.3. 90% fertilization success. Plus Environment Canada and EPA methodology","Larvae","Filtered sea water (FSW; 0.2 uM) or artificial sea water (ASW) prepared using Instant Ocean synthetic Salts (Spectrum Brands Inc). ","Static","","","","","","31 ± 1",">90%","8 ±0.15","17±1","TBBPA (tetrabromobisphenol A: CAS 79-94-7 purity 97%)"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","268-3"]
["Scores",10,10,5,5,5,5,5,5,5,4,2,0,0,4,4,3,3,3,3,3,84,0.8936170212765957,""]
["Answers","7 days","Larval development; presece of short or abnormal arms and edema ","NOEC","NOEC","Yes - solvent control (DMSO)","Yes","Yes described in Section 2.3. 90% fertilization success. Plus Environment Canada and EPA methodology","Larvae","Filtered sea water (FSW; 0.2 uM) or artificial sea water (ASW) prepared using Instant Ocean synthetic Salts (Spectrum Brands Inc). ","Static","","","","","","31 ± 1",">90%","8 ±0.15","17±1","TBBPA (tetrabromobisphenol A: CAS 79-94-7 purity 97%)"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","270-1"]
["Scores",10,5,5,5,5,5,5,5,5,4,0,0,0,4,4,3,0,0,3,3,71,0.75531914893617025,"The highest possible grade for this datum is acceptable."]
["Answers","2 days","Mortality ","LC10",0.10,"Yes - artificial seawater control","","International organization of Standards (ISO; Geneva, Switzerland).","Adult","Artificial seawater","Static","","","","","",0.18,"","","20 ± 0.5 oC","BPA (CAS 80-05-7) >97% purity"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","270-2"]
["Scores",10,5,5,5,5,5,5,5,5,4,0,0,0,4,4,3,0,0,3,3,71,0.75531914893617025,"The highest possible grade for this datum is acceptable."]
["Answers","2 days","Mortality ","LC10",0.10,"Yes - artificial seawater control","","International organization of Standards (ISO; Geneva, Switzerland).","Adult","Artificial seawater","Static","","","","","",0.18,"","","20 ± 0.5 oC","BPA (CAS 80-05-7) >97% purity"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","270-4"]
["Scores",10,10,5,5,5,5,5,5,5,4,0,0,0,4,4,3,0,0,3,3,76,0.80851063829787229,"The highest possible grade for this datum is acceptable."]
["Answers","5 days","Inhibition of development","EC10","nhibition of larval development - EC10","Yes - artificial seawater control","Yes - 12 dups for the control and 4 dups for each test concentration","International organization of Standards (ISO; Geneva, Switzerland).","Nauplii","Artificial seawater","Static","","","","","",0.18,"","","20 ± 0.5 oC","BPA (CAS 80-05-7) >97% purity"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","271-2"]
["Scores",10,10,5,5,5,5,2,5,5,4,0,0,4,4,4,3,3,3,3,3,83,0.88297872340425532,"The highest possible grade for this datum is acceptable."]
["Answers","4 days","Survival ","NOEC","NOEC - defined","Yes - solvent control with seawater","Yes - triplicate","Standard static toxicity tests","Adult","Yes - seawater UV treated natural","Static","No - not stated","No - not stated","Yes Figure 1","Yes","Yes",0.079000000000000001,"5.24 mg/L",0.32,"20 ± 1 oC","BPA 99.9% purity"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","271-3"]
["Scores",10,10,5,5,5,5,2,5,5,4,0,0,4,4,4,3,3,3,3,3,83,0.88297872340425532,"The highest possible grade for this datum is acceptable."]
["Answers","4 days","Survival ","NOEC","NOEC - defined","Yes - solvent control with seawater","Yes - triplicate","Standard static toxicity tests","Adult","Yes - seawater UV treated natural","Static","No - not stated","No - not stated","Yes Figure 1","Yes","Yes",0.079000000000000001,"5.24 mg/L",0.32,"20 ± 1 oC","BPA 99.9% purity"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","280-2"]
["Scores",10,10,5,5,5,5,0,5,5,4,0,0,4,4,4,3,0,0,3,3,75,0.7978723404255319,"The highest possible grade for this datum is acceptable."]
["Answers","25 days","","LOEC","LOEC","Yes - unfiltered seawater","Yes","","Larvae","Yes- unfiltered seawater","Flow through ","","","Figure 1","","","32 g/L","","","16-18oC","BPA (Sigma Cat# 239658)"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","744-2"]
["Scores",10,10,0,0,5,5,0,5,5,4,0,0,4,4,4,3,3,3,3,3,71,0.75531914893617025,"The highest possible grade for this datum is acceptable."]
["Answers","5 days","Metamorphosis and hatching","No - NOEC","No - NOEC","Sand filtered seawater and acetone solvent","Yes - three reps","","Adults - female","Sand filtered seawater","Static","No - not stated","No - not stated","Yes - figure 2","","","30 +/-2%","> 6.0 mg/L","8.0 +/-0.2","24+/-2oC","98.0% BPA"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","742-1"]
["Scores",10,10,5,5,5,5,2,5,5,4,0,0,4,4,4,0,0,0,3,3,74,0.78723404255319152,"The highest possible grade for this datum is acceptable."]
["Answers","3 days","cell counts","EC10",0.10,"Filtered seawater","Yes","OECD guidelines ","Adults - female","Filtered seawater supplemented with macronutrients, vitamins and trace metals","static","Not stated","Not stated","Table 2","","","","","","20oC","Analytica grade reagent; Cat no. A133027; Sigma-Aldrich"]
["Category","MEW_nonplant","Paper and data unique identifier(eg. 1-1,10-150)","742-2"]
["Scores",10,10,5,5,5,5,2,5,5,4,0,0,4,4,4,0,0,0,3,3,74,0.78723404255319152,"The highest possible grade for this datum is acceptable."]
["Answers","3 days","cell counts","EC50",0.50,"Filtered seawater","Yes","OECD guidelines ","-","Filtered seawater supplemented with macronutrients, vitamins and trace metals","static","Not stated","Not stated","Table 2","","","","","","20oC","Analytica grade reagent; Cat no. A133027; Sigma-Aldrich"]

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[null,1,"Fill in the blank cells below, based on information provided in the paper being assessed. You can either pick an option from the dropdown list or add the appropriate detail using the 'Add to list' button. ",null,null,{"$f":"IF(BA3=\"\",0,1)","v":1},null,null,null,null,null,null,null,null,"* All the text in RED are used for drop down list ,make changes with caution."]
[null,null,"Category",{"$f":"IF(AF3=\"\",0,1)","v":1},"MEW_plant",{"$f":"IF(E3=\"\",0,1)","v":1},"Citation No.",{"$f":"IF(ISERROR(FIND(\"-\",E3)),E3,LEFT(E3,FIND(\"-\",E3)-1))","v":"291"},null,"Taxonomic group",null,null,null,null,"Species",null,null,"Lifestage",null,null,"Exposure duration",null,null,"Measure of toxicity",null,null,"Toxicity endpoint",null,null,"Taxonomic group",null,null,"Phylum",null,null,"Class",null,null,"Media",null,null,"Temperature ",null,null,"Acute Or Chronic",null,null,"PH",null,null,"Salinity/Comdictivity"]
[null,null,"Paper and data unique identifier(eg. 1-1,10-150)",{"$f":"IF(AI3=\"\",0,1)","v":1},"291-2",{"$f":"IF(E4=\"\",0,1)","v":1},"Species (Scientific name)",null,null,"Phylum",null,null,null,null,"Aedes albopictus",12,{"$f":"IF(P3=0,\"\",INDEX(O3:O102,P3))","v":"Chlorella sp."},"1 month",5,{"$f":"IF(S3=0,\"\",INDEX(R3:R102,S3))","v":"N.A."},"11 hour",8,{"$f":"IF(V3=0,\"\",INDEX(U3:U102,V3))","v":"3 days"},"EC50",1,{"$f":"IF(Y3=0,\"\",INDEX(X3:X102,Y3))","v":"EC50"},"average pop growth rate: cell density",13,{"$f":"IF(AB3=0,\"\",INDEX(AA3:AA102,AB3))","v":"Growth"},"Diatom",5,{"$f":"IF(AE3=0,\"\",INDEX(AD3:AD102,AE3))","v":"N.A."},"Bacillariophyta",3,{"$f":"IF(AH3=0,\"\",INDEX(AG3:AG102,AH3))","v":"Chlorophyta"},"Branchiopoda",10,{"$f":"IF(AK3=0,\"\",INDEX(AJ3:AJ102,AK3))","v":"Trebouxiophyceae"},"F/2 marine media",10,{"$f":"IF(AN3=0,\"\",INDEX(AM3:AM102,AN3))","v":"Natural and artificial seawater"},15,8,{"$f":"IF(AQ3=0,\"\",INDEX(AP3:AP102,AQ3))","v":"N.A."},"Acute",3,{"$f":"IF(AT3=0,\"\",INDEX(AS3:AS102,AT3))","v":"N.A."},"7.5 - 8.3",3,{"$f":"IF(AW3=0,\"\",INDEX(AV3:AV102,AW3))","v":"N.A."},20,5,{"$f":"IF(AZ3=0,\"\",INDEX(AY3:AY102,AZ3))","v":"30 ppt"}]
[null,null,"Citation",{"$f":"IF(AL3=\"\",0,1)","v":1},"Walsh, G.E., M.J. Yoder, L.L. McLaughlin and E.M. Lores. 1987. Response of marine unicellular algae to brominated organic compounds in six growth media. Ecotoxicology and Environmental Safety 14: 215-222",{"$f":"IF(H8=\"\",0,1)","v":1},"Lifestage",null,null,"Class",null,null,null,null,"Australian Bass",null,null,"1 year old",null,null,"13 days",null,null,"EC50",null,null,"Average population growth rate",null,null,"Fish ",null,null,"Bacillariophyta",null,null,"Chlorophyceae",null,null,"filtered artificial seawater",null,null,20,null,null,"Chronic",null,null,"8.1–8.4",null,null,30]
[null,null,null,{"$f":"IF(AO3=\"\",0,1)","v":1},null,{"$f":"IF(AX3=\"\",0,1)","v":1},"Exposure duration",null,null,"Media",null,null,null,null,"Dunaliella tertiolecta",null,null,"Fresh culture < 7d",null,null,"24hr",null,null,"LC50",null,null,"Bioluminescence",null,null,"Macroalgae",null,null,"Chlorophyta",null,null,"Cyanophyceae",null,null,"Freshwater",null,null,25,null,null,"N.A.",null,null,"N.A.",null,null,"150 uS/cm"]
[null,null,null,{"$f":"IF(AR3=\"\",0,1)","v":1},null,{"$f":"IF(Q3=\"\",0,1)","v":1},"Measure of toxicity",null,null,"Temperature ",null,null,null,null,"Dunaliella tertiolecta",null,null,"log phase growth",null,null,"5 hours",null,null,"LOEC",null,null,"Cell density, biovolume",null,null,"Microalga",null,null,"Cyanobacteria",null,null,"Dinophyceae",null,null,"Marinewater",null,null,"15°C",null,null,null,null,null,"Not stated",null,null,"213 uS/cm"]
[null,null,null,{"$f":"IF(AU3=\"\",0,1)","v":1},null,{"$f":"IF(T3=\"\",0,1)","v":1},"Toxicity endpoint",null,null,"Acute Or Chronic ",null,null,null,null,"N.A.",null,null,"N.A.",null,null,"96 hrs",null,null,"N.A.",null,null,"Fish ",null,null,"N.A.",null,null,"Miozoa",null,null,"Mediophyceae",null,null,"N.A.",null,null,"20 ± 1°C",null,null,null,null,null,"pH 8.1–8.4",null,null,"30 ppt"]
[null,null,null,null,null,{"$f":"IF(W3=\"\",0,1)","v":1},"Toxicity value","0.83 mg/L",null,"PH",null,null,null,null,"Photobacterium phosphoreum",null,null,"N/A",null,null,"N.A.",null,null,"NOEC",null,null,"Growth inhibition",null,null,null,null,null,"N.A.",null,null,"Mediophyceae",null,null,"natural seawater",null,null,"25 ± 1",null,null,null,null,null,"PH11",null,null,"33 ± 0.5"]
[null,2,"Select the appropriate answer option to each question. Comments can be added to the cells in column H.",null,null,{"$f":"IF(Z3=\"\",0,1)","v":1},null,null,null,"Salinity/Conductivity",null,null,null,null,"Pyrocystis lunula",null,null,"not stated",null,null,"4 days",null,null,null,null,null,"Inhibition of carbon incorporation",null,null,null,null,null,"Ochrophyta",null,null,"N.A.",null,null,"Saltwater algal assay medium",null,null,"25°C",null,null,null,null,null,"PH7.0",null,null,"N.A."]
[null,"*","If the selected answer option does not work try clicking on any other cell first and then click back on the answer option again.",null,null,{"$f":"IF(AC3=\"\",0,1)","v":1},null,null,null,null,null,null,null,null,"Saccharina latissima",null,null,"Not stated",null,null,"3 days",null,null,null,null,null,"Microalga",null,null,null,null,null,"Tracheophyta",null,null,"Phaeophyceae",null,null,"Sterilised and filtered offshore marine water",null,null,"N.A.",null,null,null,null,null,null,null,null,"Not stated"]
[null,"No.","Question","Marks Awarded","Answer Options","Option References","Scores","Answers",null,null,null,null,null,null,"Skeletonema costatum",null,null,null,null,null,null,null,null,null,null,null,"N.A.",null,null,null,null,null,null,null,null,"Bacillariophyceae",null,null,"Saltwater algal assay medium",null,null,"20+/-2",null,null,null,null,null,null,null,null,"20 ppt"]
[null,null,"Was the duration of the exposure stated (e.g. 48 or 96 h)?",10,null,1,{"$f":"IF(F15=0,0,INDEX($D12:$D13,F12,1))","v":10},"3 days",null,null,null,null,null,null,"Synechococcus sp. ",null,null,null,null,null,null,null,null,null,null,null,"Population Abundance: Biomass (Chl-a)",null,null,null,null,null,null,null,null,"Trebouxiophyceae",null,null,"Natural and artificial seawater"]
[null,1,null,0,null,null,null,null,null,null,null,null,null,null,"Thalassiosira pseudonana",null,null,null,null,null,null,null,null,null,null,null,"relative growth rate"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Chlorella sp.",null,null,null,null,null,null,null,null,null,null,null,"Cell counts"]
[null,null,"Was the biological endpoint (e.g., immobilization or population growth) stated and defined (10 marks)? Award 5 marks if the biological endpoint is only stated.",10,null,1,{"$f":"IF(F15=0,0,INDEX($D15:$D17,F15,1))","v":10},"Growth - cell counts",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Growth"]
[null,2,null,5]
[null,null,null,0]
[null,null,"Was the biological effect stated (e.g. LC or NOEC)?",5,null,1,{"$f":"IF(F18=0,0,INDEX($D18:$D19,F18,1))","v":5},"EC50"]
[null,3,null,0]
[]
[null,4,"Was the biological effect quantified (e.g. 50% effect, 25% effect)? \nNote: The effect for NOEC and LOEC data must be quantified.",5,null,1,{"$f":"IF(F21=0,0,INDEX($D21:$D22,F21,1))","v":5},"EC50"]
[null,null,null,0]
[null,5,"Were appropriate controls (e.g. a no-toxicant control and/or solvent control) used?",5,null,1,{"$f":"IF(F23=0,0,INDEX($D23:$D24,F23,1))","v":5},"Natural and artificial seawater"]
[null,null,null,0]
[]
[null,6,"Was each control and contaminant concentration at least duplicated?",5,null,1,{"$f":"IF(F26=0,0,INDEX($D26:$D27,F26,1))","v":5},"Assume yes as based on Walsh and Alexander"]
[null,null,null,0]
[]
[null,7,"Were test acceptability criteria stated (e.g. mortality in controls must not exceed a certain percentage) (5 marks)?\nOR Were test acceptability criteria inferred (e.g. test method used [USEPA, OECD, ASTM etc.]) (award 2 marks). \nNote: Data that fail the acceptability criteria are automatically deemed to be of unacceptable quality and must not be used. ",5,null,3,{"$f":"IF(F29=0,0,INDEX($D29:$D31,F29,1))","v":0}]
[null,null,null,2]
[null,null,null,0]
[null,8,"Were the characteristics of the test organism (e.g. length, mass, age) stated?",5,null,1,{"$f":"IF(F32=0,0,INDEX($D32:$D34,F32,1))","v":5},"Culture source obtained"]
[null,null,null,0]
[]
[null,9,"Was the type of test media used stated?",5,null,1,{"$f":"IF(F35=0,0,INDEX($D35:$D37,F35,1))","v":5},"Natural and artificial seawater"]
[null,null,null,0]
[]
[null,null,"Was the type of exposure (e.g. static, flow through) stated? ",4,null,1,{"$f":"IF(F38=0,0,INDEX($D38:$D40,F38,1))","v":4},"Static"]
[null,10,null,0]
[]
[null,null,"Were the contaminant concentrations measured at the beginning and end of the exposure (4 marks)? Award 2 marks if they were measured only once during the test.\nNote: If the concentrations were not measured then automatically the data cannot be high quality. ",4,null,1,{"$f":"IF(F41=0,0,INDEX($D41:$D43,F41,1))","v":4},"HPLC"]
[null,11,null,2]
[null,null,null,0]
[null,null,"Were parallel reference toxicant toxicity tests conducted?",4,null,1,{"$f":"IF(F44=0,0,INDEX($D44:$D46,F44,1))","v":4},"No - not stated"]
[null,12,null,0]
[]
[null,null,"Was there a concentration–response relationship either observable or stated?",4,null,1,{"$f":"IF(F47=0,0,INDEX($D47:$D49,F47,1))","v":4}]
[null,13,null,0]
[]
[null,null,"Was an appropriate statistical method or model used to determine the toxicity?\nNote: They should be accepted by a recognised national or international regulatory body (e.g. USEPA, OECD, ASTM). ",4,null,1,{"$f":"IF(F50=0,0,INDEX($D50:$D52,F50,1))","v":4},"Yes"]
[null,14,null,0]
[]
[null,15,"For LC/EC/BEC data was an estimate of variability provided? \nOR \nFor NO EC/LOEC data was the significance level 0.05 or less?  \n\n",4,null,1,{"$f":"IF(F53=0,0,INDEX($D53:$D55,F53,1))","v":4},"Yes "]
[null,null,null,0]
[]
[null,16,"Were the following parameters measured and stated? (3 marks if measured and stated, 1 mark if just measured)."]
[null,16.10,"Conductivity/Salinity",3,null,1,{"$f":"IF(F57=0,0,INDEX(D57:D59,F57,1))","v":3},"30 ppt"]
[null,null,null,1]
[null,null,null,0]
[null,null,null,3,null,3,{"$f":"IF(F60=0,0,INDEX($D60:$D62,F60,1))","v":0}]
[null,16.20,"pH ",1]
[null,null,null,0]
[null,null,"Was the temperature measured and stated (3 marks)? Award 1 mark if the temperature was measured but not stated or if only the temperature settings of the room or chamber are stated.\n",3,null,3,{"$f":"IF(F63=0,0,INDEX($D63:$D65,F63,1))","v":0}]
[null,17,null,1]
[null,null,null,0]
[null,null,"Were test solutions, blanks and/or controls tested for contamination OR were analytical reagent grade chemicals used or the highest possible purity chemicals used for the experiment? (3 marks).",3,null,2,{"$f":"IF(F66=0,0,INDEX($D66:$D67,F66,1))","v":0}]
[null,18,null,0]
[]
[null,null,null,null,null,null,null,null,{"$f":"(COUNTIF(F12:F67,\"=0\"))+COUNTIF(F1:F10,\"=0\")+COUNTIF(D2:D7,\"=0\")","v":0}]
[]
[]
[null,null,"Total score",null,null,null,{"$f":"IF(SUM(G12:G66)=0,\"\",SUM(G12:G66))","v":77}]
[null,null,"Total Max. possible score for the various types of data and contaminants ",null,{"$f":"D12+D15+D18+D21+D23+D26+D29+D32+D35+D38+D41+D44+D47+D50+D53+D60+D63+D66+D57","v":91}]
[null,null,"Quality Score",null,{"$f":"\"= [Total score / Total possible score] * 100 = \"","v":"= [Total score / Total possible score] * 100 = "},null,{"$f":"IF(ISERROR(G72/E73),#N/A,G72/E73)","v":0.84615384615384615},{"$f":"IF(F41=3,\"The highest possible grade for this datum is acceptable.\",\"\")","v":""}]
[]
[null,null,"H = high quality                           Quality score ≥ 80%    "]
[null,null,"A = acceptable quality         > 50% Quality score < 80%  "]
[null,null,"U = unacceptable quality              Quality score ≤ 50%"]
[]
[3,null,"Click the 'Save & Update' button to save and export the answers to the 'All results' worksheet. "]
[null,null,"Select the 'Reset Answers' button if you wish to clear all answers."]

{"sheet":"MEW plant_WS","index":8,"n_rows":17,"n_cols":23,"rows_kept":17,"cut":false,"hidden":false,"merged":[]}
[]
["Question No.",1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16.10,16.30,17,18,"Total Score","Quality Score","Comment "]
["Short Questions","Duration of the exposure ","Biological endpoint","Biological effect stated or not","Biological effect quantified or not","Appropriate controls","Control & contaminant concentration","Test acceptability criteria","Characteristics of the test organism"," Type of test media","Type of exposure","Contaminant concentrations","Parallel reference toxicant toxicity tests","Concentration–response relationship","Determine the toxicity","NOEC/LOEC or LC/EC/BEC","Conductivity/Salinity","PH","Temperature","Grade or purity"]
["Marks Awarded ","10 or 0","10,5 or 0","5 or 0 ","5 or 0 ","5 or 0 ","5 or 0 ","5 or 0 ","5 or 0 ","5 or 0 ","4 or 0","4 or 2 or 0","4 or 2","4 or 2","4 or 2","4 or 2","3 or 1 or 0","3 or 1 or 0","3 or 0","3 or 0 "]
["Max. Possible Score",10,10,5,5,5,5,5,5,5,4,4,4,4,4,4,3,3,3,3,{"$f":"SUM(B5:T5)","v":91}]
["Category","MEW_plant","Paper and data unique identifier(eg. 1-1,10-150)","287-2"]
["Scores",10,10,5,5,5,5,2,5,5,4,2,0,4,4,4,1,0,0,0,77,0.84615384615384615,""]
["Answers","96 h","Chlorophyll a","EC50","50%","EPA procedures and Table 3 shows control results","EPA procedures so assume yes","EPA procedures so inferred","EPA procedures so assumed. Does state lab culture. ","Saltwater algal assay medum","Static","","","Table 3","","95% CIs provided ","","Not stated","20±2oC","Polycarbonate-grade bisphenol A, obtained from the DOW Chemical Company, Texas Division, (Freeport, TX) and identified as lot no TB 84071221. Molar purity was 99.93%"]
["Category","MEW_plant","Paper and data unique identifier(eg. 1-1,10-150)","287-1"]
["Scores",10,10,5,5,5,5,2,5,5,4,0,0,4,4,4,3,0,0,0,77,0.84615384615384615,"The highest possible grade for this datum is acceptable."]
["Answers","4 days","Cell counts","EC50","EC50","Saltwater algal assay medium","Assume yes as EPA procedures followed","EPA criteria","Lab culture","Saltwater algal assay medium","Static - EPA standard procedure","No - not stated","No - not stated","Yes Table 7","Yes","Yes ","","Not stated","20+/-2oC","Yes - 99.93%"]
["Category","MEW_plant","Paper and data unique identifier(eg. 1-1,10-150)","291-1"]
["Scores",10,10,5,5,5,5,0,5,5,4,4,0,0,4,4,3,0,0,0,69,0.75824175824175821,""]
["Answers","3 days","Growth - cell counts","EC50","EC50","Natural and artificial seawater","Assume yes as based on Walsh and Alexander","","Culture source obtained","Natural and artificial seawater","Static","HPLC","No - not stated","","Yes","Yes ","","Not stated","",""]
["Category","MEW_plant","Paper and data unique identifier(eg. 1-1,10-150)","291-2"]
["Scores",10,10,5,5,5,5,0,5,5,4,4,4,4,4,4,3,0,0,0,77,0.84615384615384615,""]
["Answers","3 days","Growth - cell counts","EC50","EC50","Natural and artificial seawater","Assume yes as based on Walsh and Alexander","","Culture source obtained","Natural and artificial seawater","Static","HPLC","No - not stated","","Yes","Yes ","","Not stated","",""]